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General Information

ITK[ENSG00000113263]

SynonymsEMT;LPFS1;LYK;PSCTK2
DescriptionIL2 inducible T-cell kinase
Chromosome5q31-q32
Database ReferenceMIM:186973 HGNC:6171 HPRD:01746 Vega:OTTHUMG00000130245 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
ITK expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell0015.261
CAF000
Endothelial cell0047.299
Macrophage002.93
melanoma00152.864
melanoma tumor001,288.858
T-cell019.42,534.609
unresolved00772.87
Displaying 21-28 of 28 results.
Comparing ITK expression between groupsFDR
Macrophage VS melanomaNS
Macrophage VS unresolved8.82657586701832e-08
T-cell VS unresolved1.20043101526452e-14
melanoma tumor VS T-cell6.87139285129684e-09
melanoma tumor VS unresolvedNS
melanoma VS T-cell2.75893129639672e-49
melanoma VS melanoma tumor1.25256808593906e-07
melanoma VS unresolved0.0355793350924129
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for ITK

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]