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Gene View

General Information

PAICS[ENSG00000128050]

SynonymsADE2;ADE2H1;AIRC;PAIS
Descriptionphosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase
Chromosome4q12
Database ReferenceMIM:172439 HGNC:8587 HPRD:01401 Vega:OTTHUMG00000160957 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE67980

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PAICS expression in each cell groupMinimum Value (Read count)Median Value (Read count)Maximum Value (Read count)
candidate PCa CTC CRPC014,269
candidate PCa CTC CSPC00.510
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)013,874
lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)0865,973
lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)01.5695
PCa cell line1903.52,415
white blood cell CRPC00.51
white blood cell healthy0150
Displaying 1-20 of 28 results.
Comparing PAICS expression between groupsFDR
PCa cell line VS white blood cell CRPC1.26026977624487e-05
PCa cell line VS white blood cell healthy2.86038766707033e-07
candidate PCa CTC CRPC VS PCa cell lineNS
candidate PCa CTC CRPC VS candidate PCa CTC CSPCNS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
candidate PCa CTC CRPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
candidate PCa CTC CRPC VS white blood cell CRPCNS
candidate PCa CTC CRPC VS white blood cell healthyNS
candidate PCa CTC CSPC VS PCa cell line4.13921030420002e-17
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A)3.1753516214127e-07
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)3.43677989240065e-09
candidate PCa CTC CSPC VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)0.00339356212971974
candidate PCa CTC CSPC VS white blood cell CRPCNS
candidate PCa CTC CSPC VS white blood cell healthyNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS PCa cell lineNS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CRPC progressed on enzalutamide (Group B)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS lineage-confirmed PCa CTC CSPC enzalutamide-naive (Group A)NS
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell CRPC0.0340368871684646
lineage-confirmed PCa CTC CRPC enzalutamide-naive (Group A) VS white blood cell healthyNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PAICS

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others