| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2658 |
Name | GDF2 |
Synonym | BMP-9|BMP9;growth differentiation factor 2;GDF2;growth differentiation factor 2 |
Definition | GDF-2|bone morphogenetic protein 9|growth/differentiation factor 2 |
Position | 10q11.22 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells. |
PAH | BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 productionin pulmonary arterial hypertension. |
PH | Supplemental Table 1: A list of genes and functional categories that comprises a PHrelevant gene module (PH-module). |
| More detail of all Human literatures about GDF2 | |
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Pathways and Diseases |
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Pathway | TGF-beta signaling pathway;PANTHER;P00052 |
Pathway | ALK1 signaling events;PID Curated;200126 |
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External Links |
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Links to Entrez Gene | 2658 |
Links to all GeneRIF Items | 2658 |
Links to iHOP | 2658 |
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Sequence Information |
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Nucleotide Sequence |
>2658 : length: 1290 atgtgtcctggggcactgtgggtggccctgcccctgctgtccctgctggctggctcccta caggggaagccactgcagagctggggacgagggtctgctgggggaaacgcccacagccca ctgggggtgcctggaggtgggctgcctgagcacaccttcaacctgaagatgtttctggag aacgtgaaggtggatttcctgcgcagccttaacctgagtggggtcccttcgcaggacaaa accagggtggagccgccgcagtacatgattgacctgtacaacaggtacacgtccgataag tcgactacgccagcgtccaacattgtgcggagcttcagcatggaagatgccatctccata actgccacagaggacttccccttccagaagcacatcttgctcttcaacatctccattcct aggcatgagcagatcaccagagctgagctccgactctatgtctcctgtcaaaatcacgtg gacccctctcatgacctgaaaggaagcgtggtcatttatgatgttctggatggaacagat gcctgggatagtgctacagagaccaagaccttcctggtgtcccaggacattcaggatgag ggctgggagaccttggaagtgtccagcgccgtgaagcgctgggtccggtccgactccacc aagagcaaaaataagctggaagtgactgtggagagccacaggaagggctgcgacacgctg gacatcagtgtccccccaggttccagaaacctgcccttctttgttgtcttctccaatgac cacagcagtgggaccaaggagaccaggctggagctgagggagatgatcagccatgaacaa gagagcgtgctcaagaagctgtccaaggacggctccacagaggcaggtgagagcagtcac gaggaggacacggatggccacgtggctgcggggtcgactttagccaggcggaaaaggagc gccggggctggcagccactgtcaaaagacctccctgcgggtaaacttcgaggacatcggc tgggacagctggatcattgcacccaaggagtatgaagcctacgagtgtaagggcggctgc ttcttccccttggctgacgatgtgacgccgacgaaacacgctatcgtgcagaccctggtg catctcaagttccccacaaaggtgggcaaggcctgctgtgtgcccaccaaactgagcccc atctccgtcctctacaaggatgacatgggggtgcccaccctcaagtaccattacgagggc atgagcgtggcagagtgtgggtgcaggtag |
Protein Sequence |
>2658 : length: 429 MCPGALWVALPLLSLLAGSLQGKPLQSWGRGSAGGNAHSPLGVPGGGLPEHTFNLKMFLE NVKVDFLRSLNLSGVPSQDKTRVEPPQYMIDLYNRYTSDKSTTPASNIVRSFSMEDAISI TATEDFPFQKHILLFNISIPRHEQITRAELRLYVSCQNHVDPSHDLKGSVVIYDVLDGTD AWDSATETKTFLVSQDIQDEGWETLEVSSAVKRWVRSDSTKSKNKLEVTVESHRKGCDTL DISVPPGSRNLPFFVVFSNDHSSGTKETRLELREMISHEQESVLKKLSKDGSTEAGESSH EEDTDGHVAAGSTLARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGC FFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEG MSVAECGCR |