| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 51554 |
Name | CCRL1 |
Synonym | CC-CKR-11|CCBP2|CCR-11|CCR10|CCR11|CCX CKR|CCX-CKR|CKR-11|PPR1|VSHK1;chemokine (C-C motif) receptor-like 1;CCRL1;chemokine (C-C motif) receptor-like 1 |
Definition | C-C CKR-11|C-C chemokine receptor type 11|CC chemokine receptor-like 1|chemocentryx chemokine receptor|chemokine, cc motif, receptor-like protein 1|orphan seven-transmembrane receptor, chemokine related |
Position | 3q22 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | "We observed linkage evidence in four regions: 3q22 ([median log of the odds (LOD) = 3.43]), 3p12 (median LOD) = 2.35), 2p22 (median LOD = 2.21), and 13q21 (median LOD = 2.09). When used in conjunction with the non-parametric bootstrap, our approach yields high-resolution to identify candidate gene regions containing putative BMPR2-interacting genes. Imputation of the disease model by LOD-score maximization indicates that the 3q22 locus alone predicts most FPAH cases in BMPR2 mutation carriers, providing strong evidence that BMPR2 and the 3q22 locus interact epistatically." |
| More detail of all Human literatures about CCRL1 | |
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Pathways and Diseases |
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Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Chemokine receptors bind chemokines;PID Reactome;500406 |
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External Links |
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Links to Entrez Gene | 51554 |
Links to all GeneRIF Items | 51554 |
Links to iHOP | 51554 |
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Sequence Information |
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Nucleotide Sequence |
>51554 : length: 1053 atggctttggaacagaaccagtcaacagattattattatgaggaaaatgaaatgaatggc acttatgactacagtcaatatgaactgatctgtatcaaagaagatgtcagagaatttgca aaagttttcctccctgtattcctcacaatagttttcgtcattggacttgcaggcaattcc atggtagtggcaatttatgcctattacaagaaacagagaaccaaaacagatgtgtacatc ctgaatttggctgtagcagatttactccttctattcactctgcctttttgggctgttaat gcagttcatgggtgggttttagggaaaataatgtgcaaaataacttcagccttgtacaca ctaaactttgtctctggaatgcagtttctggcttgtatcagcatagacagatatgtggca gtaactaaagtccccagccaatcaggagtgggaaaaccatgctggatcatctgtttctgt gtctggatggctgccatcttgctgagcataccccagctggttttttatacagtaaatgac aatgctaggtgcattcccattttcccccgctacctaggaacatcaatgaaagcattgatt caaatgctagagatctgcattggatttgtagtaccctttcttattatgggggtgtgctac tttatcacagcaaggacactcatgaagatgccaaacattaaaatatctcgacccctaaaa gttctgctcacagtcgttatagttttcattgtcactcaactgccttataacattgtcaag ttctgccgagccatagacatcatctactccctgatcaccagctgcaacatgagcaaacgc atggacatcgccatccaagtcacagaaagcatcgcactctttcacagctgcctcaaccca atcctttatgtttttatgggagcatctttcaaaaactacgttatgaaagtggccaagaaa tatgggtcctggagaagacagagacaaagtgtggaggagtttccttttgattctgagggt cctacagagccaaccagtacttttagcatttaa |
Protein Sequence |
>51554 : length: 350 MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNS MVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYT LNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVND NARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLK VLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNP ILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI |