| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 59272 |
Name | ACE2 |
Synonym | ACEH;angiotensin I converting enzyme (peptidyl-dipeptidase A) 2;ACE2;angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
Definition | ACE-related carboxypeptidase|angiotensin I converting enzyme 2|angiotensin-converting enzyme 2|angiotensin-converting enzyme homolog|metalloprotease MPROT15 |
Position | Xp22 |
Gene Type | protein-coding |
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PAH Type |
Description |
PAH | results demonstrated that activation of ACE2 by continuous injection of resorcinolnaphthalein prevented the development of pulmonary arterial hypertension through improving early endothelial dysfunction. |
PAH | results demonstrated that activation of ACE2 by continuous injection of resorcinolnaphthalein prevented the development of pulmonary arterial hypertension through improving early endothelial dysfunction. |
| More detail of all Rat literatures about ACE2 | |
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Pathways and Diseases |
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Pathway | Renin-angiotensin system;KEGG PATHWAY;hsa04614 |
Pathway | Protein digestion and absorption;KEGG PATHWAY;hsa04974 |
Disease | Hypertension;FunDO |
Disease | blood pressure, arterial;GAD |
Disease | hypertension;GAD |
Disease | Proteinuria;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Coronavirus infection;FunDO |
Disease | PHARMACOGENOMIC;GAD |
Disease | Sarcoidosis;FunDO |
Disease | Kidney disease;FunDO |
Disease | left ventricular hypertrophy;GAD |
Disease | Acute Coronary Syndrome;GAD |
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External Links |
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Links to Entrez Gene | 59272 |
Links to all GeneRIF Items | 59272 |
Links to iHOP | 59272 |
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Sequence Information |
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Nucleotide Sequence |
>59272 : length: 2418 atgtcaagctcttcctggctccttctcagccttgttgctgtaactgctgctcagtccacc attgaggaacaggccaagacatttttggacaagtttaaccacgaagccgaagacctgttc tatcaaagttcacttgcttcttggaattataacaccaatattactgaagagaatgtccaa aacatgaataatgctggggacaaatggtctgcctttttaaaggaacagtccacacttgcc caaatgtatccactacaagaaattcagaatctcacagtcaagcttcagctgcaggctctt cagcaaaatgggtcttcagtgctctcagaagacaagagcaaacggttgaacacaattcta aatacaatgagcaccatctacagtactggaaaagtttgtaacccagataatccacaagaa tgcttattacttgaaccaggtttgaatgaaataatggcaaacagtttagactacaatgag aggctctgggcttgggaaagctggagatctgaggtcggcaagcagctgaggccattatat gaagagtatgtggtcttgaaaaatgagatggcaagagcaaatcattatgaggactatggg gattattggagaggagactatgaagtaaatggggtagatggctatgactacagccgcggc cagttgattgaagatgtggaacatacctttgaagagattaaaccattatatgaacatctt catgcctatgtgagggcaaagttgatgaatgcctatccttcctatatcagtccaattgga tgcctccctgctcatttgcttggtgatatgtggggtagattttggacaaatctgtactct ttgacagttccctttggacagaaaccaaacatagatgttactgatgcaatggtggaccag gcctgggatgcacagagaatattcaaggaggccgagaagttctttgtatctgttggtctt cctaatatgactcaaggattctgggaaaattccatgctaacggacccaggaaatgttcag aaagcagtctgccatcccacagcttgggacctggggaagggcgacttcaggatccttatg tgcacaaaggtgacaatggacgacttcctgacagctcatcatgagatggggcatatccag tatgatatggcatatgctgcacaaccttttctgctaagaaatggagctaatgaaggattc catgaagctgttggggaaatcatgtcactttctgcagccacacctaagcatttaaaatcc attggtcttctgtcacccgattttcaagaagacaatgaaacagaaataaacttcctgctc aaacaagcactcacgattgttgggactctgccatttacttacatgttagagaagtggagg tggatggtctttaaaggggaaattcccaaagaccagtggatgaaaaagtggtgggagatg aagcgagagatagttggggtggtggaacctgtgccccatgatgaaacatactgtgacccc gcatctctgttccatgtttctaatgattactcattcattcgatattacacaaggaccctt taccaattccagtttcaagaagcactttgtcaagcagctaaacatgaaggccctctgcac aaatgtgacatctcaaactctacagaagctggacagaaactgttcaatatgctgaggctt ggaaaatcagaaccctggaccctagcattggaaaatgttgtaggagcaaagaacatgaat gtaaggccactgctcaactactttgagcccttatttacctggctgaaagaccagaacaag aattcttttgtgggatggagtaccgactggagtccatatgcagaccaaagcatcaaagtg aggataagcctaaaatcagctcttggagataaagcatatgaatggaacgacaatgaaatg tacctgttccgatcatctgttgcatatgctatgaggcagtactttttaaaagtaaaaaat cagatgattctttttggggaggaggatgtgcgagtggctaatttgaaaccaagaatctcc tttaatttctttgtcactgcacctaaaaatgtgtctgatatcattcctagaactgaagtt gaaaaggccatcaggatgtcccggagccgtatcaatgatgctttccgtctgaatgacaac agcctagagtttctggggatacagccaacacttggacctcctaaccagccccctgtttcc atatggctgattgtttttggagttgtgatgggagtgatagtggttggcattgtcatcctg atcttcactgggatcagagatcggaagaagaaaaataaagcaagaagtggagaaaatcct tatgcctccatcgatattagcaaaggagaaaataatccaggattccaaaacactgatgat gttcagacctccttttag |
Protein Sequence |
>59272 : length: 805 MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQ NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTIL NTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQ AWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILM CTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKS IGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLH KCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK NSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKN QMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDN SLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENP YASIDISKGENNPGFQNTDDVQTSF |