| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1491 |
Name | CTH |
Synonymous | -;cystathionase (cystathionine gamma-lyase);CTH;cystathionase (cystathionine gamma-lyase) |
Definition | cystathionine gamma-lyase|cysteine desulfhydrase|cysteine-protein sulfhydrase|gamma-cystathionase|homoserine deaminase|homoserine dehydratase |
Position | 1p31.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
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Link to UCSC genome |
Matched SNP location |
dbSNP ID |
Regulatory information |
chr1:70876901-70905534 | chr1:70876959-70876959 | rs17131292 | Single_Nucleotides|eQTL|HHLA3, Chromatin_Structure|FAIRE|Gm19239, Chromatin_Structure|FAIRE|Gliobla, Chromatin_Structure|DNase-seq|Helas3Ifna4h, Chromatin_Structure|FAIRE|Gm12891, Chromatin_Structure|DNase-seq|Gliobla, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|FAIRE|Gm12892, Chromatin_Structure|DNase-seq|Aosmc, Chromatin_Structure|DNase-seq|Cll, Chromatin_Structure|DNase-seq|Hepg2, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Htr8, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Panisd, Chromatin_Structure|DNase-seq|A549, Chromatin_Structure|DNase-seq|Stellate, Chromatin_Structure|FAIRE|K562, Chromatin_Structure|DNase-seq|Urotsa, Chromatin_Structure|FAIRE|Helas3, Chromatin_Structure|DNase-seq|Fibrobl, Chromatin_Structure|DNase-seq|Gm12878, Chromatin_Structure|DNase-seq|Fibrop, Chromatin_Structure|FAIRE|H1hesc, Chromatin_Structure|DNase-seq|Chorion, Chromatin_Structure|DNase-seq|Helas3, Chromatin_Structure|DNase-seq|Myometr, Chromatin_Structure|DNase-seq|Nhek, Chromatin_Structure|DNase-seq|Huh7, Chromatin_Structure|DNase-seq|Panislets, Chromatin_Structure|FAIRE|Gm18507, Chromatin_Structure|DNase-seq|Huvec, Chromatin_Structure|DNase-seq|Hpde6e6e7, Chromatin_Structure|DNase-seq|Huh75, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Progfib, Chromatin_Structure|FAIRE|Huvec, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Gm18507, Chromatin_Structure|DNase-seq|Mcf7, Chromatin_Structure|DNase-seq|Gm19238, Chromatin_Structure|DNase-seq|Melano, Chromatin_Structure|DNase-seq|T47d, Chromatin_Structure|DNase-seq|Gm12891, Chromatin_Structure|DNase-seq|Hsmm, Chromatin_Structure|DNase-seq|Gm19239, Chromatin_Structure|DNase-seq|Gm19240, Chromatin_Structure|DNase-seq|Gm12892, Chromatin_Structure|DNase-seq|K562, Chromatin_Structure|FAIRE|Nhek, Chromatin_Structure|DNase-seq|Phte, Chromatin_Structure|FAIRE|Hepg2, Chromatin_Structure|DNase-seq|H9es, Chromatin_Structure|DNase-seq|Hmec, Chromatin_Structure|DNase-seq|Hsmmt, Chromatin_Structure|DNase-seq|Lncap, Chromatin_Structure|DNase-seq|Medullo, Chromatin_Structure|DNase-seq|Ips, Chromatin_Structure|DNase-seq|UrotsaUt189, Chromatin_Structure|DNase-seq|8988t, Chromatin_Structure|DNase-seq|H1hesc, Chromatin_Structure|FAIRE|Htr8, Chromatin_Structure|FAIRE|Mcf7, Chromatin_Structure|DNase-seq|Hepatocytes, Protein_Binding|ChIP-seq|ETS1, Protein_Binding|ChIP-seq|CDX2, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TRIM28, Protein_Binding|ChIP-seq|NFYB, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|NFYA, Protein_Binding|ChIP-seq|MAX, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|GTF2F1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|MYC, Protein_Binding|ChIP-seq|RFX5, Protein_Binding|ChIP-seq|SP1, Protein_Binding|ChIP-seq|SP1, Protein_Binding|ChIP-seq|EP300, Protein_Binding|ChIP-seq|FOS, Protein_Binding|ChIP-seq|CCNT2, Protein_Binding|ChIP-seq|CHD2, Protein_Binding|ChIP-seq|HMGN3, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|GATA1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|HEY1, Protein_Binding|ChIP-seq|HEY1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TBP, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|TAF1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POU2F2, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|SIN3A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|MAX, Protein_Binding|ChIP-seq|REST, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|E2F6, Protein_Binding|ChIP-seq|SIN3A, Protein_Binding|ChIP-seq|TAF7, Protein_Binding|ChIP-seq|MXI1, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A, Protein_Binding|ChIP-seq|POLR2A | chr1:70876901-70905534 | chr1:70877779-70877779 | rs487773 | Single_Nucleotides|eQTL|CTH, Chromatin_Structure|FAIRE|Gm12878, Chromatin_Structure|DNase-seq|Aosmc |
|---|---|---|---|
Transcription Factors [Top] |
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Regulation From TransFac database |
CTH(h) --> cystathionine gamma-lyase isoform-1(h) (expression). | 2 cystathionine gamma-lyase(h) <==> (cystathionine gamma-lyase(h))2 (binding) | CTH(h) --> cystathionine gamma-lyase(h) (expression). | CTH(h) --> cystathionine gamma-lyase isoform-2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
282 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr1 |
Promoter: 70648043 - 70650043 | Agilent_014791 |
chr1 |
Promoter: 70648043 - 70650043 | GSE27584 |
chr1 |
Promoter: 70648043 - 70650043 | GSE27584 |
chr1 |
Promoter: 70648043 - 70650043 | Agilent_014791_44K |