Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3351

Name

HTR1B

Synonymous

5-HT1B|5-HT1DB|HTR1D2|HTR1DB|S12;5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled;HTR1B;5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Definition

5-HT-1B|5-HT-1D-beta|5-hydroxytryptamine receptor 1B|serotonin 1D beta receptor|serotonin receptor 1B

Position

6q13

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for HTR1B

Transcription Factors   [Top]

Regulation From TransFac database

NDPKB(h) + 5-HT-1B(h) <==> NDPKB(h):5-HT-1B(h) (binding)
hGSTK1(h) + 5-HT-1B(h) <==> hGSTK1(h):5-HT-1B(h) (binding)
HTR1B(h) --> 5-HT-1B(h) (expression).
HTR1B(h) --> 5-HT-1B(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

24N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
32N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
388S-palmitoyl cysteine (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr6

Promoter: 78229339 - 78231339Agilent_014791

chr6

Promoter: 78229339 - 78231339GoldenGate_Methylation_Cancer_Panel_I

chr6

Promoter: 78229339 - 78231339GSE27584

chr6

Promoter: 78229339 - 78231339Agilent_014791_44K

chr6

Promoter: 78229339 - 78231339PMID:11709722

chr6

Promoter: 78229339 - 78231339PMID:16435073


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