| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 5617 |
Name | PRL |
Synonymous | -;prolactin;PRL;prolactin |
Definition | decidual prolactin |
Position | 6p22.2-p21.3 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for PRL | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
prolactin(h) + CypB(h) <==> prolactin(h):CypB(h) (binding) | prolactin(h) --> prolactin(h) (translocation) | prolactin(h) --> prolactin(h) (translocation) | prolactin(h) + STAT5A(r) <==> prolactin(h):STAT5A(r) (binding) | prolactin(h) --> prolactin-p17(h) + protein remnants (cleavage) | prolactin(h) --> prolactin-p15(h) + protein remnants (cleavage) | prolactin(h) --> prolactin-p11(h) + protein remnants (cleavage) | prolactin(h) --> prolactin-p8(h) + protein remnants (cleavage) | prl(h) --> prolactin(h) (expression). | prolactin(h) --> prolactin(h) (translocation) | prolactin(h) --> prolactin(h) (translocation) | prolactin(h) --> Fyn(r){pY} (increase of phosphorylation) | prolactin(h) --> PRLR-S(r){pY} (increase of phosphorylation) | prolactin(h) --> PRLR-L(r){pY} (increase of phosphorylation) | prolactin(h) --> ERK1(h){p} (increase of phosphorylation) | prolactin(h) --> ERK2(h){p} (increase of phosphorylation) | prolactin(h) --> p38alpha(h){p} (increase of phosphorylation) | prolactin(h) --> JNK1(h){p} (increase of phosphorylation) | prolactin(h) --> JNK2(h){p} (increase of phosphorylation) | prolactin(h) --> ERK1(r){p} (increase of phosphorylation) | prolactin(h) --> ERK2(r){p} (increase of phosphorylation) | prolactin(h) --> prolactin-p11(h) + protein remnants (cleavage) | prolactin(h) --> prolactin-p15(h) + protein remnants (cleavage) | prolactin(h) --> prolactin-p17(h) + protein remnants (cleavage) | prolactin(h) --cathepsin-D(h)--> prolactin-p17(h) + protein remnants (cleavage) | prolactin(h) --cathepsin-D(h)--> prolactin-p15(h) + protein remnants (cleavage) | prolactin(h) --cathepsin-D(h)--> prolactin-p11(h) + protein remnants (cleavage) | prolactin(h) --cathepsin-D(h)--> prolactin-p8(h) + protein remnants (cleavage) | prolactin(h) --> STAT5(h){pY} (increase of phosphorylation) | prolactin(h) --/ SOCS-3(h) (decrease of abundance) | prolactin(h) --> Jak1(h){pY} (increase of phosphorylation) | prolactin(h) --> Jak2(h){pY} (increase of phosphorylation) | prolactin(h) --> STAT5B(h){pY} (increase of phosphorylation) | prolactin(h) --> STAT3(h){p} (increase of phosphorylation) | prolactin(h) --> STAT1(h){p} (increase of phosphorylation) | prl(h) --> prolactin(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
59 | N-linked (GlcNAc...); partial. | Swiss-Prot 53.0 | 194 | Phosphoserine | 15687336 | Phospho.ELM 6.0 | 163 | Phosphoserine | 15687336 | Phospho.ELM 6.0 | 207 | Phosphoserine (PAK2) | 11943200 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for PRL | ||