Found 209 literature records

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Entrez ID	Description
2134	"Recently, the EXTL1 gene, a member of the EXT tumor suppressor gene family, has been mapped to 1p36, a chromosome region which is frequently implicated in a wide variety of malignancies, including breast carcinoma, colorectal cancer and neuroblastoma. "
324	Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
324	"Asef, a link between the tumor suppressor APC and G-protein signaling."
324	Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis.
324	Apical membrane localization of the adenomatous polyposis coli tumor suppressor protein and subcellular distribution of the beta-catenin destruction complex in polarized epithelial cells.
8915	These data suggest that wild-type BCL10 may act as a tumor suppressor.
4763	"Neurofibromin, a tumor suppressor in the nervous system."
324	Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the adenomatous polyposis coli (APC) tumor suppressor gene.
1630	"Interaction of Myc-associated zinc finger protein with DCC, the product of a tumor-suppressor gene, during the neural differentiation of P19 EC cells."
1029	Evaluation of alterations in the tumor suppressor genes INK4A and INK4B in human bladder tumors.
1030	Evaluation of alterations in the tumor suppressor genes INK4A and INK4B in human bladder tumors.
324	Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene.
324	Structure of the amino-terminal nuclear export domain of the APC tumor suppressor protein.
7157	investigated whether Tat might alter p53 acetylation and p53-responsive transcription; results allude to mechanism where the HIV-1 trans-activator might impair tumor suppressor functions favoring establishment of neoplasia in AIDS
665	"Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer."
9353	SLIT2 is an excellent candidate tumor suppressor gene for colorectal cancer.
219699	UNC5H may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
8633	may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
90249	may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis
8406	"down-regulation of drs mRNA is closely correlated with carcinomas which arise from adenomatous polyps in the course of the adenoma-carcinoma sequence, but most carcinomas arising de novo are independent of the tumor suppressor function of the drs gene"
6392	SDHD may have a role in colorectal and gastric cancers as a distinct type of tumor suppressor
9314	KLF4 is a tumor suppressor in colorectal cancer.
1316	Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.
4089	Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of Croatian patients: identification of a novel somatic mutation.
8651	These findings suggested that SOCS-1 may act as a tumor suppressor in at least some colorectal cancers and that SOCS-1 methylation may be a particular phenomenon related to a nearly onset of colorectal cancer.
1316	Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein.
5728	"We found that indomethacin and NS-398 treatment significantly upregulated expression of the tumor suppressor gene, PTEN."
324	Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity.
1002	CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis
634	The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis.
3400	ID4 gene is a potential tumor suppressor gene for which methylation status may play an important role in the CRC progression
5268	maspin tumor suppressor expression is induced by p53 or TAp63gamma
7157	maspin tumor suppressor expression is induced by p53 or TAp63gamma
55615	"Thus, PRR5 may represent a potential candidate tumor suppressor gene in breast cancer"
324	The APC tumor suppressor promotes transcription-independent apoptosis in vitro.
3678	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
3688	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
1029	Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues.
4436	"Tumor suppressor gene, hMSH2, may play an important role as a putative coactivator in ER alpha dependent gene expression."
9770	RASSF2 is a novel tumor suppressor gene that regulates Ras signaling and plays a pivotal role in the early stages of colorectal tumorigenesis.
2932	Our findings demonstrate an unrecognized role of GSK3beta in tumor cell survival and proliferation other than its predicted role as a tumor suppressor.
1316	Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers.
57575	"Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation."
324	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
4221	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
5783	The PTPN13 protein has proapoptotic functions and can fuction as TSGs to suppress tumorigenesis.
324	The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.
1316	KLF6 gene may be one of the candidate tumor suppressor genes in colorectal cancers and that genetic alteration of the KLF6 gene might play a role in the development of colorectal carcinomas.
1630	Automated quantitative analysis of DCC tumor suppressor protein in ovarian cancer tissue microarray shows association with beta-catenin levels and outcome in patients with epithelial ovarian cancer.
2050	"Study provides evidence showing that promoter methylation regulates EPHB4 transcription and that EPHB4 can regulate the long-term clonogenic potential of colorectal tumor cells, revealing EPHB4 as a potential tumor suppressor gene in colorectal cancer."

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