Found 484 literature records

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Entrez ID	Description
4771	Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas: s study of 20 cases.
4013	The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
23705	The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer.
91768	ik3-1/Cables has been identified to be a candidate tumor suppressor for colon and head/neck cancers.
10395	DLC-1 plays a role in non-small cell lung carcinoma by acting as a bona fide new tumor suppressor gene.
650	BMP2 acts as a tumor suppressor promoting apoptosis in mature colonic epithelial cells.
9314	KLF4 is a tumor suppressor in colorectal cancer.
160728	"Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids."
5371	Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
11186	RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma
1316	Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer.
4089	Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of Croatian patients: identification of a novel somatic mutation.
51741	The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
11186	The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
10210	"topors functions as a negative regulator of cell growth, and possibly as a tumor suppressor"
51364	"BLU, a candidate tumor suppressor gene, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma."
9093	an important cell death regulator and could exert tumor suppressor activity
5925	Docking-dependent regulation of the Rb tumor suppressor protein by Cdk4.
1316	Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.
324	The tumor suppressor adenomatous polyposis coli and caudal related homeodomain protein regulate expression of retinol dehydrogenase L.
857	"Results suggest different roles for CAV1 in SCLC, where CAV1 acts like a tumor suppressor gene, and NSCLC, where it appears required for survival and growth."
5795	"A candidate tumor suppressor gene because its expression was blocked in rat and human thyroid transformed cells, and its restoration reverted their neoplastic phenotype."
5728	"We found that indomethacin and NS-398 treatment significantly upregulated expression of the tumor suppressor gene, PTEN."
324	Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity.
545	ATR serves as a haploinsufficient tumor suppressor in mismatch repair-deficient cells
4015	"LOX is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in gastric cancers, and possibly also in other cancers."
1026	Tumor suppressor functions for the Cdk inhibitor p21 in the mouse colon.
2131	Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells.
324	The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF.
4771	"MAP, a protein interacting with a tumor suppressor, merlin, through the run domain."
324	Tumor suppressor APC blocks DNA polymerase beta-dependent strand displacement synthesis during long patch but not short patch base excision repair and increases sensitivity to methylmethane sulfonate.
1002	CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis
634	The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis.
3400	ID4 gene is a potential tumor suppressor gene for which methylation status may play an important role in the CRC progression
22943	"DKK-1 expression decreases in human colon tumors, suggesting that DKK-1 acts as a tumor suppressor gene in this neoplasia; the Wnt/beta-catenin pathway is downregulated by the induction of DKK-1 expression, a mechanism that is lost in colon cancer"
3621	Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras.
11337	GABARAP mRNA expression and protein expression were significantly down-regulated in invasive ductal and invasive lobular carcinomas; GABARAP acts via a vesicle transport mechanism as a tumor suppressor in breast cancer.
324	Status of reduced expression and hypermethylation of the APC tumor suppressor gene in human oral squamous cell carcinoma.
324	The APC tumor suppressor promotes transcription-independent apoptosis in vitro.
3678	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
3688	integrin alpha5/beta1 exerts its tumor suppressor-like activity in colon cancer cells by inhibiting HER-2 signaling
1029	Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues.
324	This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP).
347252	IGFBP-RP4 may be a novel putative tumor suppressor protein.
56849	"TCEAL7 is a cell death regulatory protein that is frequently inactivated in ovarian cancers, and may function as a tumor suppressor."
4436	"Tumor suppressor gene, hMSH2, may play an important role as a putative coactivator in ER alpha dependent gene expression."
4763	"NF1 tumor suppressor gene is a direct transcriptional target of RUNX1 and the t(8;21) fusion protein, suggesting that suppression of NF1 expression contributes to the molecular pathogenesis of acute myeloid leukemia ."
6422	"SFRP 1 gene is frequently downregulated by promoter hypermethylation and suppresses tumor growth activity of lung cancer cells, which suggests that SFRP 1 is a candidate tumor suppressor gene for lung cancer"
4771	Merlin can function as a tumor suppressor by inhibiting the RalGDS-mediated oncogenic signals.
9770	RASSF2 is a novel tumor suppressor gene that regulates Ras signaling and plays a pivotal role in the early stages of colorectal tumorigenesis.

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