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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 10297 |
Name | APC2 |
Synonym | APCL;adenomatosis polyposis coli 2;APC2;adenomatosis polyposis coli 2 |
Definition | adenomatous polyposis coli like|adenomatous polyposis coli protein 2 |
Position | 19p13.3 |
Gene Type | protein-coding |
Source | Count: 1; TAG |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
| . |
| More detail of all 0 literatures about APC2 | |
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Pathways and Diseases |
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Pathway | Wnt signaling pathway;KEGG PATHWAY;hsa04310 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Endometrial cancer;KEGG PATHWAY;hsa05213 |
Pathway | Basal cell carcinoma;KEGG PATHWAY;hsa05217 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Colorectal cancer;KEGG PATHWAY;hsa05210 |
Disease | Colorectal cancer;KEGG DISEASE;H00020 |
Disease | Cancers;KEGG DISEASE |
Disease | Cancers of the digestive system;KEGG DISEASE |
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External Links |
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Links to Entrez Gene | 10297 |
Links to all GeneRIF Items | 10297 |
Links to iHOP | 10297 |
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Sequence Information |
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Nucleotide Sequence |
>10297 : length: 6912 atggcgagctccgtggcgccctacgagcagctggtgaggcaggtggaggccttgaaggct gagaacagccacctgaggcaggagctaagggacaactccagccacctgtccaagctggag acagagacgtcgggcatgaaggaggtcctgaagcacctacagggaaaactggagcaggag gcccgagtgctggtgtcctcggggcagacggaggtgctggagcagctgaaggccctacag atggacatcaccagcctgtacaacctcaagttccagccgcccaccctgggcccggagcct gccgcccggacccccgagggcagcccagtacacggctccgggccctccaaggacagcttt ggggagctgagccgggccaccatccggctgctggaggaactggaccgggaacggtgtttc ctgctgaatgagattgagaaggaggagaaggagaagctctggtactactctcagctgcag ggcctgtccaagcgcctggacgagctgccgcacgtggagacgcagttctcgatgcagatg gacctgatccggcagcagcttgagttcgaggcccagcacatccgctcgctgatggaggag cgcttcggcacctcggacgagatggtgcagcgggcacagatccgcgcctcgcgcctggag cagattgacaaggagctgctggaggcgcaggaccgagtgcagcagacggagccccaggcc ttgctggcggtgaagtcggtgccggtggacgaggaccccgagacagaggtccccacacac cctgaggatggcacccctcagccgggcaacagcaaggtggaggtggtcttctggctgttg tccatgttggcgacgcgcgaccaggaggatacagcgcgcacgctgctggccatgtccagc tcgcccgagagctgcgtggccatgcgccgctcgggctgtctgcctctgctgctgcaaatc ctccacggcaccgaggccgcggccgggggtcgcgccggggccccaggggcaccgggcgcc aaggacgcacgcatgcgcgccaacgcggcgctgcacaacatcgtcttctcgcagccggac cagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcagatccgggcctac tgcgagacctgctgggactggctgcaggcccgagacggcgggcccgagggaggtggcgcc ggcagcgccccgatccccatcgagccgcagatctgccaggccacctgtgctgttatgaag ctgtcctttgatgaggagtaccgccgtgccatgaacgagctaggtgggctgcaggccgtg gcagagctgctgcaggttgactatgagatgcacaagatgacccgggacccgctgaacctg gcgctgcgccgctacgcgggcatgaccctcaccaacctcacctttggggacgttgccaac aaggccaccctgtgtgcgcgccgcggctgcatggaggccatcgtggcccagctggcctcc gacagtgaggagctccaccaggtggtgtccagcatccttcggaacttgtcctggagggcc gacatcaacagcaagaaggtgctgagggaggcgggcagcgtgactgccctggtgcagtgt gtcctgcgggccaccaaggagtccaccctgaagagcgtgctgagcgccctgtggaatctg tctgcacacagcacagagaacaaggcggccatctgccaggtggatggcgccctgggcttc ctggtgagcaccctgacctacaagtgtcagagcaactcgctggccatcatcgagagcggc ggcggcatcctccgcaatgtgtccagcctcgtcgccacccgtgaggactacaggcaggtg ctccgggatcacaactgtctgcagacgctgctgcagcatctgacttcgcacagcctgacc atcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagcgcccgtgaccag gagctgctgtgggacctgggcgccgtgggcatgctgcgtaatctggtgcactccaagcac aagatgatcgccatgggcagcgccgccgccctgcgcaacctgctggcccatcggcccgcc aagcaccaggcggccgccaccgccgtgtccccaggcagctgcgtgcccagcctgtacgtg cgcaagcagcgggcgctggaggccgagctggacgcacggcacctcgcgcaggcgctggag cacctggagaagcagggcccgccggcagccgaggccgccactaagaagccgctgccgccc ctgcgacacctggacggcctggcccaagactatgcttccgattcgggctgctttgacgac gacgatgcaccgtcatccctggctgcggccgcggccaccggggagccagccagccctgcc gcgctgtccctcttcctgggcagccccttcctgcaggggcaggcgctggctcgcaccccg cccacccgccgaggcggcaaggaggcagagaaggacaccagtggggaggcagccgtggcg gccaaggccaaggccaagctggcgcttgcagtggcgcgcatcgaccagctggtggaggac atctccgccctgcacacctcgtccgacgatagcttcagcctcagctctggagacccggga caggaggcgccacgggagggccgcgcccagtcctgctcgccatgccgcggcccggagggc gggcggcgagaggcaggaagccgggcgcacccgctgctgcggctcaaggcggcccacgcc agcctctccaacgacagcctcaacagcggcagtgccagcgacgggtactgcccacgcgaa catatgctgccctgcccgctggccgcactggcttcgcgccgcgaggaccccaggtgtggg cagcctcggcccagccggcttgaccttgacctgcccggctgccaggccgagcccccggcc cgcgaggccacctccgccgacgcccgcgtgcgcaccatcaagctgtcgcctacctatcag cacgtgccactgcttgagggtgcctcaagggcgggtgcagagcccctcgcggggcctgga atctctccaggggcccggaagcaggcctggctgccggcagaccacctgagcaaggttccc gagaagctggcggctgccccgctgtctgtggccagcaaggcactgcagaaactggcggcg caagaggggccactctcgctgtcccgatgcagctccctttcctcgctgtcctcggccggc cgcccaggccccagcgagggtggtgacctggatgacagtgactcctccctggaggggctg gaggaggccggccccagcgaggctgagctggacagcacgtggcgggcgcccggggccacc tcgctgcccgtagccattccggctccccggcgtaaccgaggccggggcctgggggtggaa gacgccacgccgtccagctcgtcggagaactacgtgcaggagacaccgcttgtgctgagc cgctgcagctctgtgagctcgctgggcagcttcgagagcccgtccatcgccagctccatc cccagtgaaccttgcagcgggcagggcagcggcaccatcagccctagcgagctgcccgac agccccggacagaccatgcctcccagccggagcaagacgccaccgctggcgcccgcgcca cagggtccccccgaggccacccagttcagcctgcagtgggagagctacgtgaagcgcttc ctggacatcgccgactgccgggagcgctgccggctgccatctgagctggacgcaggcagc gtgcgctttaccgtggagaagccagacgagaacttctcgtgcgcctccagcctcagcgcg ctggccttgcacgagcactacgtgcagcaggacgtggagctgcggctgctgccctcggcc tgccccgagcgcggcgggggcgccgggggcgccggcctccactttgcagggcaccggcgg cgggaggaggggccggcgcccacgggttctcgccctcgcggcgccgcggaccaggagctg gaactgctgcgggagtgcctgggagccgccgtgcctgcccggctgcgcaaggtggcctcc gcgctggtgccaggtcgccgcgcactccccgtgcccgtctacatgttggtgcccgccccg gccccggcccaggaggacgactcctgcactgactccgcggagggcacgccggtcaacttc tctagcgccgcctcgctcagcgacgagacgctgcagggaccccccagggaccagcccggg ggaccagcgggcaggcaaagacccaccggccgccccacctctgccagacaggccatgggg caccggcacaaggcgggaggcgccggccgcagcgcggagcagtctcggggcgcgggcaag aacagagcagggctggagctgcccctgggccggcccccgagcgcccccgcagacaaggac ggctcaaagcccggccggacccgcggggacggggcgctccagtcgctgtgcctcacgacg cccactgaggaggccgtgtactgcttctacggcaacgactcggacgaggagcccccggcg gccgcgcccacgccaacccaccggcgcacatcggccatccctcgcgcttttacgcgggag cgtccgcagggccggaaggaggcccctgccccgtccaaggctgcaccagctgccccgccg cccgcccggacccagcccagcctcattgctgacgagaccccgccctgctactccctgagc tcctccgccagctccctcagcgagcccgagccctcggagccgccggccgtccatccacga ggccgggagcccgcggtcaccaaggacccgggcccaggaggcggacgcgacagctcgccc agcccgcgggccgcggaggagcttctgcagcggtgcatcagctcggccctgcccaggcgc cggccccccgtgtctggcctgcggcgccgcaagccccgagccacccggctggatgagcgg cccgcagaggggtcccgggaacgcggcgaggaggcagcgggctcggaccgggcctccgac ctggatagcgtggagtggcgcgccatccaggagggcgccaattcaattgtcacgtggctg caccaggcagcagctgccacgcgggaggcctcgtccgagtccgactccatcctgtccttc gtatccgggctgtcagtgggatccaccctacagccccccaagcacaggaagggacgacag gcggagggagaaatgggcagtgcccggcggccagagaaaaggggcgcagcctcagtcaag accagcgggagcccccgttcccctgcaggccccgagaagccacgtggcacacagaagacc acgcccggggtgccagctgtgctccggggacgaacagtgatctacgtccccagcccggca ccccgtgcccagcccaaagggacccccggcccccgcgccacaccgcggaaggtggcgccc ccttgcctggcacagcccgcggctccagccaaagtcccgagccccgggcagcagcggtcg cggagcctacaccggcctgccaagacctcggagctggcgacgctgagccagccccccaga agcgccacaccgcccgcccgcctcgccaagaccccctcctccagctcctcccagacctcg cccgcctcccagcccctgcccagaaagcgccccccggtcacccaggctgctggggccctg cccggccccggagcctccccggtgcccaaaacgccggcgcgcacccttctggcgaagcag cacaagacgcagagatcgcccgtgcggatcccgttcatgcagaggccggcccggcgtggg ccgccaccgctggctcgggcagtcccggagccgggccccaggggccgggcggggaccgag gcgggcccgggggcgcgcgggggccgcctgggcctggtgcgtgtggcctcagccctctcc agcggcagcgagtcctccgaccgctcgggcttccggcgacagctaaccttcatcaaggag tcgccgggcttgcggcgccgccgctccgagctgtcctcggccgagtccgcggcctctgcc ccccagggcgcctcgccccgccgcggccggcccgcgctgcccgccgtcttcctctgctcc tcgcgctgcgaagagctccgagcggcaccccggcagggcccggccccggcccggcagcgg ccccccgcggcccgacccagccctggcgagcgccctgcccggcgcaccacctccgagagc ccgtcccgcctgcctgtgcgcgcgcccgccgcccggccggagactgtcaagcgctacgcg tcgctgccgcacatcagcgtggcccgcaggcccgacggcgccgtccccgcggcccctgcc tcagccgacgccgcgcgccgcagcagcgacggggagccccggccgctccccagggtggcc gcgccgggcacgacctggcggcgcatccgagatgaggacgtgccccacatcctgcgcagc acgcttcccgccacggccctgccactgcggggctccacgcccgaggacgccccggccggg cccccgccgcgcaagaccagcgacgccgtggtccagaccgaggaggtcgccgcccccaag accaactccagcacgtccccgagcctggagaccagggagccccccggggcccccgccggc ggccagctctccctcctcggcagcgacgtggacggtcccagcctcgccaaggctcccatc tccgcacccttcgtgcacgagggcctgggggtcgccgtggggggcttccccgccagccgg cacggctcccccagccgctcggcccgagtaccccccttcaactatgtgcccagccccatg gtggtcgcagccaccaccgactcggccgcggagaaagccccggccactgcctccgccacc ctcctggaatag |
Protein Sequence |
>10297 : length: 2303 MASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQE ARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPTLGPEPAARTPEGSPVHGSGPSKDSF GELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQM DLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQA LLAVKSVPVDEDPETEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSS SPESCVAMRRSGCLPLLLQILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPD QGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSAPIPIEPQICQATCAVMK LSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVAN KATLCARRGCMEAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQC VLRATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESG GGILRNVSSLVATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQ ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKHQAAATAVSPGSCVPSLYV RKQRALEAELDARHLAQALEHLEKQGPPAAEAATKKPLPPLRHLDGLAQDYASDSGCFDD DDAPSSLAAAAATGEPASPAALSLFLGSPFLQGQALARTPPTRRGGKEAEKDTSGEAAVA AKAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEG GRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPREHMLPCPLAALASRREDPRCG QPRPSRLDLDLPGCQAEPPAREATSADARVRTIKLSPTYQHVPLLEGASRAGAEPLAGPG ISPGARKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLSSLSSAG RPGPSEGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVE DATPSSSSENYVQETPLVLSRCSSVSSLGSFESPSIASSIPSEPCSGQGSGTISPSELPD SPGQTMPPSRSKTPPLAPAPQGPPEATQFSLQWESYVKRFLDIADCRERCRLPSELDAGS VRFTVEKPDENFSCASSLSALALHEHYVQQDVELRLLPSACPERGGGAGGAGLHFAGHRR REEGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAP APAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGRQRPTGRPTSARQAMG HRHKAGGAGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRTRGDGALQSLCLTT PTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPP PARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSP SPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASD LDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQ AEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPA PRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPR SATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQ HKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALS SGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCS SRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYA SLPHISVARRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRS TLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAG GQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSPM VVAATTDSAAEKAPATASATLLE |