Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

10912

Name

GADD45G

Synonym

CR6|DDIT2|GADD45gamma|GRP17;growth arrest and DNA-damage-inducible, gamma;GADD45G;growth arrest and DNA-damage-inducible, gamma

Definition

DDIT-2|DNA damage-inducible transcript 2 protein|GADD45-gamma|cytokine-responsive protein CR6|gadd-related protein, 17 kD|growth arrest and DNA damage-inducible protein GADD45 gamma

Position

9q22.1-q22.2

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

potential

Results show that GADD45G can act as a functional new-age tumor suppressor but being frequently inactivated epigenetically in multiple tumors.
More detail of all 1 literatures about GADD45G

Pathways and Diseases

Pathway

IL12-mediated signaling events;PID Curated;200034

Pathway

Cell cycle;KEGG PATHWAY;hsa04110

Pathway

p53 pathway;PANTHER;P00059

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

p53 signaling pathway;KEGG PATHWAY;hsa04115

Disease

Pituitary tumor;FunDO

Disease

Liver cancer;FunDO

Disease

protein quantitative trait loci;GAD

Disease

Protein quantitative trait loci;NHGRI

External Links

Links to Entrez Gene

10912

Links to all GeneRIF Items

10912

Links to iHOP

10912

Sequence Information

Nucleotide Sequence

>10912 : length: 480
atgactctggaagaagtccgcggccaggacacagttccggaaagcacagccaggatgcag
ggtgccgggaaagcgctgcatgagttgctgctgtcggcgcagcgtcagggctgcctcact
gccggcgtctacgagtcagccaaagtcttgaacgtggaccccgacaatgtgaccttctgt
gtgctggctgcgggtgaggaggacgagggcgacatcgcgctgcagatccattttacgctg
atccaggctttctgctgcgagaacgacatcgacatagtgcgcgtgggcgatgtgcagcgg
ctggcggctatcgtgggcgccggcgaggaggcgggtgcgccgggcgacctgcactgcatc
ctcatttcgaaccccaacgaggacgcctggaaggatcccgccttggagaagctcagcctg
ttttgcgaggagagccgcagcgttaacgactgggtgcccagcatcaccctccccgagtga

Protein Sequence

>10912 : length: 159
MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
LISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE



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