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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 23047 |
Name | PDS5B |
Synonym | APRIN|AS3|CG008;PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae);PDS5B;PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) |
Definition | androgen induced inhibitor of proliferation|androgen-induced proliferation inhibitor|androgen-induced prostate proliferative shutoff-associated protein AS3|androgen-induced shutoff 3|sister chromatid cohesion protein PDS5 homolog B |
Position | 13q12.3 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | APRIN/Pds5B is lost in many cancers and it is a putative tumor suppressor. |
potential | "We mapped the complete BRCA2 deletion, which extends over at least 298 kb and showed that it does not affect APRIN/AS3, previously characterized as a tumor suppressor gene, but it comprises several loci corresponding to proven or putative transcripts of unknown functional significance." |
| More detail of all 2 literatures about PDS5B | |
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External Links |
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Links to Entrez Gene | 23047 |
Links to all GeneRIF Items | 23047 |
Links to iHOP | 23047 |
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Sequence Information |
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Nucleotide Sequence |
>23047 : length: 4344 atggctcattcaaagactaggaccaatgatggaaaaattacatatccgcctggggtcaag gaaatatcagataaaatatctaaagaggagatggtgagacgattaaagatggttgtgaaa acttttatggatatggaccaggactctgaagaagaaaaggagctttatttaaacctagct ttacatcttgcttcagatttttttctcaagcatcctgataaagatgttcgcttactggta gcctgctgccttgctgatattttcaggatttatgctcctgaagctccttacacatcccct gataaactaaaggatatatttatgtttataacaagacagttgaaggggctagaggataca aagagcccacaattcaataggtatttttatttacttgagaacattgcttgggtcaagtca tataacatatgctttgagttagaagatagcaatgaaattttcacccagctatacagaacc ttattttcagttataaacaatggccacaatcagaaagtccatatgcacatggtagacctt atgagctctattatttgtgaaggtgatacagtgtctcaggagcttttggatacggtttta gtaaatctggtacctgctcataagaatttaaacaagcaagcatatgatttggcaaaggct ttactgaagaggacagctcaagctattgagccatatattaccaatttttttaatcaggtt ctgatgcttgggaaaacatctatcagcgatttgtcagagcatgtctttgacttaattttg gagctctacaatattgatagtcatttgctgctctctgttttaccccagcttgaatttaaa ttaaagagcaatgataatgaggagcgcctacaagttgttaaactactggcaaaaatgttt ggggcaaaggattcagaattggcttctcaaaacaagccactttggcagtgctacttgggc aggtttaatgatatccatgtaccaatccgcctggaatgtgtgaaatttgctagccattgt ctcatgaaccatcctgatttagcaaaagacttaacagagtatcttaaagtgaggtcacat gaccctgaggaagctattagacatgatgttattgtgtcaatagttacagctgctaaaaag gatattcttctggtcaatgatcacttacttaattttgtgagagagagaacattagacaaa cgatggagagtacgcaaagaagccatgatgggacttgcccaaatttataagaaatatgct ttacagtcagcagctggaaaagatgctgcaaaacagatagcatggatcaaagacaaattg ctacatatatattatcaaaatagtattgatgatcgactacttgttgaacggatctttgct caatacatggttcctcacaatttagaaactacagaacggatgaaatgcttatattacttg tatgccacactggatttaaatgctgtgaaagcattgaatgaaatgtggaaatgtcaaaat ctgctccgacatcaagtaaaggatttgcttgacttgattaagcaacccaaaacagatgcc agtgtcaaggccatattttcaaaagtgatggttattacaagaaatttacctgatcctggt aaggctcaggatttcatgaagaaattcacacaggtgttagaagatgatgagaaaataaga aagcagttagaagtacttgttagtccaacatgctcctgcaagcaggctgaaggttgtgtg cgtgaaataactaagaagttgggcaaccccaaacagcctacaaatcctttcctggaaatg atcaagtttctcttggagaggatagcacctgtgcacatagataccgaatctatcagtgct cttattaaacaagtgaacaaatcaatagatggaacagcagatgatgaagatgagggtgtt ccaactgatcaagccatcagagcaggtcttgaactgcttaaggtactctcatttacacat cccatctcatttcattctgctgaaacatttgaatcattactggcttgtctgaaaatggat gatgaaaaagtagcagaagctgcactacaaattttcaaaaacacaggaagcaaaattgaa gaggattttccacacatcagatcagccttgcttcctgttttacatcacaaatctaaaaaa ggacccccccgtcaagccaaatatgccattcattgtatccatgcgatattttctagtaaa gagacccagtttgcacagatatttgagcctctgcataagagcctagatccaagcaacctg gaacatctcataacaccattggttactattggtcatattgctctccttgcacctgatcaa tttgctgctcctttgaaatctttggtagctactttcattgtgaaagatcttctcatgaat gatcggcttccagggaaaaagacaactaaactttgggttccagatgaagaagtatctcct gagacaatggtcaaaattcaggctattaaaatgatggttcgatggctacttggaatgaaa aataatcacagtaaatcaggaacttctaccttaagattgctaacaacaatattgcatagt gatggagacttgacagaacaggggaaaattagtaaaccagatatgtcacgtctgagactt gctgctgggagtgctattgtgaagctggcacaagaaccctgttaccatgaaatcatcaca ttagaacaatatcagctatgtgcattagctatcaacgatgaatgctatcaagtaagacaa gtgtttgcccagaaacttcacaaaggcctttcccgtttacggcttccacttgagtatatg gcaatctgtgccctttgtgcaaaagatcctgtaaaggagagaagagctcatgctaggcaa tgtttggtgaaaaatataaatgtaaggcgggagtatctgaagcagcatgcagctgttagt gaaaaattattgtctcttctaccagagtatgttgttccatatacaattcaccttttggca catgacccagattatgtcaaagtacaggatattgaacaacttaaagatgttaaagaatgt ctttggtttgttctggaaatattaatggctaaaaatgaaaataacagtcacgcttttatc agaaagatggtagaaaatattaaacaaacaaaagatgcccaaggaccagatgatgcaaaa atgaatgaaaaactgtacactgtgtgtgatgttgccatgaatatcatcatgtcaaagagt actacatacagtttggaatctcctaaagacccggtactaccagctcgtttcttcactcaa cctgacaagaatttcagtaacaccaaaaattatctgcctcctgaaatgaaatcatttttc actcctggaaaacctaaaacaaccaatgttctaggagctgttaacaagccactttcatca gcaggcaagcaatctcagaccaaatcatcacgaatggaaactgtaagcaatgcaagcagc agctcaaatccaagctctcctggaagaataaaggggaggcttgatagttctgaaatggat cacagtgaaaatgaagattacacaatgtcttcacctttgccggggaaaaaaagtgacaag agagacgactctgatcttgtaaggtctgaattggagaagcctagaggcaggaaaaaaacg cccgtcacagaacaggaggagaaattaggtatggatgacttgactaagttggtacaggaa cagaaacctaaaggcagtcagcgaagtcggaaaagaggccatacggcttcagaatctgat gaacagcagtggcctgaggaaaagaggctcaaagaagatatattagaaaatgaagatgaa cagaatagtccgccaaaaaagggtaaaagaggccgaccaccaaaacctcttggtggaggt acaccaaaagaagagccaacaatgaaaacttctaaaaaaggaagcaaaaaaaaatctgga cctccagcaccagaggaggaggaagaagaagaaagacaaagtggaaatacggaacagaag tccaaaagcaaacagcaccgagtgtcaaggagagcacagcagagagcagaatctcctgaa tctagtgcaattgaatccacacagtccacaccacagaaaggacgaggaagaccatcaaaa acgccatcaccatcacaaccaaaaaaaaatgtccgtgtaggacgctccaaacaagcagct actaaggaaaatgattcaagtgaagaagtagatgtgtttcagggtagctctcctgtcgat gatattccacaggaagaaacagaggaggaggaagtttctacagtaaatgtacggcggcga agtgctaaaagggaacggcgatga |
Protein Sequence |
>23047 : length: 1447 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR SAKRERR |