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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 5610 |
Name | EIF2AK2 |
Synonym | EIF2AK1|PKR|PRKR;eukaryotic translation initiation factor 2-alpha kinase 2;EIF2AK2;eukaryotic translation initiation factor 2-alpha kinase 2 |
Definition | P1/eIF-2A protein kinase|double stranded RNA activated protein kinase|eIF-2A protein kinase 2|interferon-induced, double-stranded RNA-activated protein kinase|interferon-inducible elF2alpha kinase|p68 kinase|protein kinase, interferon-inducible double str |
Position | 2p22-p21 |
Gene Type | protein-coding |
Source | Count: 1; TAG |
Literature support | Count: 0 PubMed records as below. |
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Evidence Status |
Description |
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| More detail of all 0 literatures about EIF2AK2 | |
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Pathways and Diseases |
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Pathway | Influenza Infection;Reactome;REACT:6167 |
Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | inactivation of gsk3 by akt causes accumulation of b-catenin in alveolar macrophages;PID BioCarta;100152 |
Pathway | regulation of eif2;PID BioCarta;100179 |
Pathway | toll-like receptor pathway;PID BioCarta;100013 |
Pathway | Ceramide signaling pathway;PID Curated;200100 |
Pathway | double stranded rna induced gene expression;PID BioCarta;100040 |
Pathway | Inhibition of PKR;PID Reactome;500919 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Protein processing in endoplasmic reticulum;KEGG PATHWAY;hsa04141 |
Disease | INFECTION;GAD |
Disease | hepatitis C;GAD |
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External Links |
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Links to Entrez Gene | 5610 |
Links to all GeneRIF Items | 5610 |
Links to iHOP | 5610 |
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Sequence Information |
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Nucleotide Sequence |
>5610 : length: 1656 atggctggtgatctttcagcaggtttcttcatggaggaacttaatacataccgtcagaag cagggagtagtacttaaatatcaagaactgcctaattcaggacctccacatgataggagg tttacatttcaagttataatagatggaagagaatttccagaaggtgaaggtagatcaaag aaggaagcaaaaaatgccgcagccaaattagctgttgagatacttaataaggaaaagaag gcagttagtcctttattattgacaacaacgaattcttcagaaggattatccatggggaat tacataggccttatcaatagaattgcccagaagaaaagactaactgtaaattatgaacag tgtgcatcgggggtgcatgggccagaaggatttcattataaatgcaaaatgggacagaaa gaatatagtattggtacaggttctactaaacaggaagcaaaacaattggccgctaaactt gcatatcttcagatattatcagaagaaacctcagtgaaatctgactacctgtcctctggt tcttttgctactacgtgtgagtcccaaagcaactctttagtgaccagcacactcgcttct gaatcatcatctgaaggtgacttctcagcagatacatcagagataaattctaacagtgac agtttaaacagttcttcgttgcttatgaatggtctcagaaataatcaaaggaaggcaaaa agatctttggcacccagatttgaccttcctgacatgaaagaaacaaagtatactgtggac aagaggtttggcatggattttaaagaaatagaattaattggctcaggtggatttggccaa gttttcaaagcaaaacacagaattgacggaaagacttacgttattaaacgtgttaaatat aataacgagaaggcggagcgtgaagtaaaagcattggcaaaacttgatcatgtaaatatt gttcactacaatggctgttgggatggatttgattatgatcctgagaccagtgatgattct cttgagagcagtgattatgatcctgagaacagcaaaaatagttcaaggtcaaagactaag tgccttttcatccaaatggaattctgtgataaagggaccttggaacaatggattgaaaaa agaagaggcgagaaactagacaaagttttggctttggaactctttgaacaaataacaaaa ggggtggattatatacattcaaaaaaattaattcatagagatcttaagccaagtaatata ttcttagtagatacaaaacaagtaaagattggagactttggacttgtaacatctctgaaa aatgatggaaagcgaacaaggagtaagggaactttgcgatacatgagcccagaacagatt tcttcgcaagactatggaaaggaagtggacctctacgctttggggctaattcttgctgaa cttcttcatgtatgtgacactgcttttgaaacatcaaagtttttcacagacctacgggat ggcatcatctcagatatatttgataaaaaagaaaaaactcttctacagaaattactctca aagaaacctgaggatcgacctaacacatctgaaatactaaggaccttgactgtgtggaag aaaagcccagagaaaaatgaacgacacacatgttag |
Protein Sequence |
>5610 : length: 551 MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSK KEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQ CASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSG SFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAK RSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKY NNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTK CLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNI FLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAE LLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWK KSPEKNERHTC |