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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 634 |
Name | CEACAM1 |
Synonym | BGP|BGP1|BGPI;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein);CEACAM1;carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
Definition | CD66a antigen|antigen CD66|carcinoembryonic antigen-related cell adhesion molecule 1 |
Position | 19q13.2 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 5 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Direct interaction of tumor suppressor CEACAM1 with beta catenin: identification of key residues in the long cytoplasmic domain. |
reviewed | data reveal the dual role of CEACAM1 on hepatocarcinogenesis; CEACAM1 acts as tumor suppressor in HepG2 cells in anchorage-depend. growth conditions; in anchorage-independent growth cond it augments cell proliferation by potentiating cell-cell attachment. |
reviewed | The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis. |
reviewed | inhibition of prostate tumor angiogenesis by the tumor suppressor CEACAM1. |
potential | "C-CAM1, a candidate tumor suppressor gene, is abnormally expressed in primary lung cancers." |
| More detail of all 5 literatures about CEACAM1 | |
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External Links |
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Links to Entrez Gene | 634 |
Links to all GeneRIF Items | 634 |
Links to iHOP | 634 |
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Sequence Information |
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Nucleotide Sequence |
>634 : length: 1395 atggggcacctctcagccccacttcacagagtgcgtgtaccctggcaggggcttctgctc acagcctcacttctaaccttctggaacccgcccaccactgcccagctcactactgaatcc atgccattcaatgttgcagaggggaaggaggttcttctccttgtccacaatctgccccag caactttttggctacagctggtacaaaggggaaagagtggatggcaaccgtcaaattgta ggatatgcaataggaactcaacaagctaccccagggcccgcaaacagcggtcgagagaca atataccccaatgcatccctgctgatccagaacgtcacccagaatgacacaggattctac accctacaagtcataaagtcagatcttgtgaatgaagaagcaactggacagttccatgta tacccggagctgcccaagccctccatctccagcaacaactccaaccctgtggaggacaag gatgctgtggccttcacctgtgaacctgagactcaggacacaacctacctgtggtggata aacaatcagagcctcccggtcagtcccaggctgcagctgtccaatggcaacaggaccctc actctactcagtgtcacaaggaatgacacaggaccctatgagtgtgaaatacagaaccca gtgagtgcgaaccgcagtgacccagtcaccttgaatgtcacctatggcccggacaccccc accatttccccttcagacacctattaccgtccaggggcaaacctcagcctctcctgctat gcagcctctaacccacctgcacagtactcctggcttatcaatggaacattccagcaaagc acacaagagctctttatccctaacatcactgtgaataatagtggatcctatacctgccac gccaataactcagtcactggctgcaacaggaccacagtcaagacgatcatagtcactgag ctaagtccagtagtagcaaagccccaaatcaaagccagcaagaccacagtcacaggagat aaggactctgtgaacctgacctgctccacaaatgacactggaatctccatccgttggttc ttcaaaaaccagagtctcccgtcctcggagaggatgaagctgtcccagggcaacaccacc ctcagcataaaccctgtcaagagggaggatgctgggacgtattggtgtgaggtcttcaac ccaatcagtaagaaccaaagcgaccccatcatgctgaacgtaaactataatgctctacca caagaaaatggcctctcacctggggccattgctggcattgtgattggagtagtggccctg gttgctctgatagcagtagccctggcatgttttctgcatttcgggaagaccggcagctca ggaccactccaatga |
Protein Sequence |
>634 : length: 464 MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ QLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFY TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWI NNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTP TISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCH ANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWF FKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALP QENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGSSGPLQ |