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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 79728 |
Name | PALB2 |
Synonym | FANCN|PNCA3;partner and localizer of BRCA2;PALB2;partner and localizer of BRCA2 |
Definition | - |
Position | 16p12.2 |
Gene Type | protein-coding |
Source | Count: 2; Generif,UniProt |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. |
| More detail of all 1 literatures about PALB2 | |
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Pathways and Diseases |
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Pathway | Fanconi Anemia pathway;PID Reactome;500068 |
Pathway | DNA Repair;Reactome;REACT:216 |
Disease | Hematologic diseases;KEGG DISEASE |
Disease | PSYCH;GAD |
Disease | Fanconi's anemia;FunDO |
Disease | Prostate cancer;FunDO |
Disease | Primary tumor;FunDO |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | breast cancer;GAD |
Disease | Embryoma;FunDO |
Disease | Breast cancer, susceptibility to;OMIM |
Disease | CANCER;GAD |
Disease | Fanconi anemia, complementation group N;OMIM |
Disease | Bipolar disorder;NHGRI |
Disease | Fanconi anemia;KEGG DISEASE;H00238 |
Disease | bipolar disorder;GAD |
Disease | Breast cancer;FunDO |
Disease | Pancreatic cancer, susceptibility to, 3;OMIM |
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External Links |
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Links to Entrez Gene | 79728 |
Links to all GeneRIF Items | 79728 |
Links to iHOP | 79728 |
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Sequence Information |
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Nucleotide Sequence |
>79728 : length: 3561 atggacgagcctcccgggaagcccctcagctgtgaggagaaggaaaagttaaaggagaaa ttagcattcttgaaaagggaatacagcaagacactagcccgccttcagcgtgcccaaaga gctgaaaagattaagcattctattaagaaaacagtagaagaacaagattgtttgtctcag caggatctctcaccgcagctaaaacactcagaacctaaaaataaaatatgtgtttatgac aagttacacatcaaaacccatcttgatgaagaaactggagaaaagacatctatcacactt gatgttgggcctgagtcctttaaccctggagatggcccaggaggattacctatacaaaga acagatgacacccaagaacattttccccacagggtcagtgaccctagtggtgagcaaaag cagaagctgccaagcagaagaaagaagcagcagaagaggacatttatttcacaggagaga gactgtgtctttggcactgattcactcagattgtctgggaaaagactaaaggaacaggaa gaaatcagtagcaaaaatcctgctagatcaccagtaactgaaataagaactcacctttta agtcttaaatctgaacttccagattctccagaaccagttacagaaattaatgaagacagt gtattaattccaccaactgcccaaccagaaaaaggtgttgatacattcctaagaagacct aatttcaccagggcgactacagttcctttacagactctatcagatagcggtagtagtcag caccttgaacacattcctcctaaaggtagcagtgaacttactactcacgacctaaaaaac attagatttacttcacctgtaagtttggaggcacaaggcaaaaaaatgactgtctctaca gataacctccttgtaaataaagctataagtaaaagtggccaactgcccacaagttctaat ttagaggcaaatatttcatgttctctaaatgaactcacctacaataacttaccagcaaat gaaaaccaaaacttaaaagaacaaaatcaaacagagaaatctttaaaatctcccagtgac actcttgatggcaggaatgaaaatcttcaggaaagtgagattctaagtcaacctaagagt cttagcctggaagcaacctctcctctttctgcagaaaaacattcttgcacagtgcctgaa ggccttctgtttcctgcagaatattatgttagaacaacacgaagcatgtccaattgccag aggaaagtagccgtggaggctgtcattcagagtcatttggatgtcaagaaaaaagggttt aaaaataaaaataaggatgcaagtaaaaatttaaacctttccaatgaggaaactgaccaa agtgaaattaggatgtctggcacatgcacaggacaaccaagttcaagaacctctcagaaa cttctctcattaactaaagtcagctctcccgctgggcccactgaagataatgacttgtct aggaaggcagttgcccaagcacctggtagaagatacacaggaaaaagaaaatcagcctgc accccagcatcagatcattgtgaaccacttttgccaacttctagcctgtcgattgttaac aggtccaaggaagaagtcacctcacacaaatatcagcacgaaaaattatttattcaagtg aaagggaagaaaagtcgtcatcaaaaagaggattccctttcttggagtaatagtgcttat ttatccttggatgatgatgctttcacggctccatttcatagggatggaatgctgagttta aagcaactactgtcttttctcagtatcacagactttcagttacctgatgaagactttgga cctcttaagcttgaaaaagtgaagtcctgctcagaaaaaccagtggagccctttgagtca aaaatgtttggagagagacatcttaaagagggaagctgtatttttccagaggaactgagt cctaaacgcatggatacagaaatggaggacttagaagaggaccttattgttctaccagga aaatcacatcccaaaaggccaaactcgcaaagccagcatacaaagacgggcctttcttca tccatattactttatactcctttaaatacggttgcgcctgatgataatgacaggcctacc acagacatgtgttcacctgctttccccatcttaggtactactccagcctttggccctcaa ggctcctatgaaaaagcatctacagaagttgctggacgaacttgctgcacaccccaactt gctcatttgaaagactcagtctgtcttgccagtgatactaaacaattcgacagttcaggc agcccagcaaaaccacataccaccctgcaagtgtcaggcaggcaaggacaacctacctgt gactgtgactctgtcccgccaggaacacctccacccattgagtcattcacttttaaagaa aatcagctctgtagaaacacatgccaggagctgcataaacattccgtcgaacagactgaa acagcagagcttcctgcttctgatagcataaacccaggcaacctacaattggtttcagag ttaaagaatccttcaggttcctgttccgtagatgtgagtgccatgttttgggaaagagcc ggttgtaaagagccatgtatcataactgcttgcgaagatgtagtttctctttggaaagct ctggatgcttggcagtgggaaaaactttatacctggcacttcgcagaggttccagtatta cagatagttccagtgcctgatgtgtataatctcgtgtgtgtagctttgggaaatttggaa atcagagagatcagggcattgttttgttcctctgatgatgaaagtgaaaagcaagtacta ctgaagtctggaaatataaaagctgtgcttggcctgacaaagaggaggctagttagtagc agtgggaccctttctgatcaacaagtagaagtcatgacgtttgcagaagatggaggaggc aaagaaaaccaatttttgatgccccctgaggagactatactaacttttgctgaggtccaa gggatgcaagaagctctgcttggtactactattatgaacaacattgttatttggaattta aaaactggtcaactcctgaaaaagatgcacattgatgattcttaccaagcttcagtctgt cacaaagcctattctgaaatggggcttctctttattgtcctgagtcatccctgtgccaaa gagagtgagtcgttgcgaagccctgtgtttcagctcattgtgattaaccctaagacgact ctcagcgtgggtgtgatgctgtactgtcttcctccagggcaggctggcaggttcctggaa ggtgacgtgaaagatcactgtgcagcagcaatcttgacttctggaacaattgccatttgg gacttacttctcggtcagtgtactgccctcctcccacctgtctctgaccaacattggtct tttgtgaaatggtcgggtacagactctcatttgctggctggacaaaaagatggaaatata tttgtataccactattcataa |
Protein Sequence |
>79728 : length: 1186 MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQ QDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQR TDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQE EISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRP NFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVST DNLLVNKAISKSGQLPTSSNLEANISCSLNELTYNNLPANENQNLKEQNQTEKSLKSPSD TLDGRNENLQESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQ RKVAVEAVIQSHLDVKKKGFKNKNKDASKNLNLSNEETDQSEIRMSGTCTGQPSSRTSQK LLSLTKVSSPAGPTEDNDLSRKAVAQAPGRRYTGKRKSACTPASDHCEPLLPTSSLSIVN RSKEEVTSHKYQHEKLFIQVKGKKSRHQKEDSLSWSNSAYLSLDDDAFTAPFHRDGMLSL KQLLSFLSITDFQLPDEDFGPLKLEKVKSCSEKPVEPFESKMFGERHLKEGSCIFPEELS PKRMDTEMEDLEEDLIVLPGKSHPKRPNSQSQHTKTGLSSSILLYTPLNTVAPDDNDRPT TDMCSPAFPILGTTPAFGPQGSYEKASTEVAGRTCCTPQLAHLKDSVCLASDTKQFDSSG SPAKPHTTLQVSGRQGQPTCDCDSVPPGTPPPIESFTFKENQLCRNTCQELHKHSVEQTE TAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKA LDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVL LKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQ GMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAK ESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIW DLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS |