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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 90249 |
Name | UNC5A |
Synonym | UNC5H1;unc-5 homolog A (C. elegans);UNC5A;unc-5 homolog A (C. elegans) |
Definition | netrin receptor UNC5A|netrin receptor Unc5h1|protein unc-5 homolog 1|protein unc-5 homolog A|unc-5 homolog 1|unc5 (C.elegans homolog) a |
Position | 5q35.2 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | may represent tumor suppressor that inhibit tumor extension outside the region of netrin-1 availability by inducing apoptosis. |
| More detail of all 1 literatures about UNC5A | |
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Pathways and Diseases |
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Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Role of DCC in regulating apoptosis;PID Reactome;500280 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
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External Links |
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Links to Entrez Gene | 90249 |
Links to all GeneRIF Items | 90249 |
Links to iHOP | 90249 |
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Sequence Information |
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Nucleotide Sequence |
>90249 : length: 2529 atggccgtccggcccggcctgtggccagcgctcctgggcatagtcctcgccgcttggctc cgcggctcgggtgcccagcagagtgccaccgtggccaacccagtgcctggtgccaacccg gacctgcttccccacttcctggtggagcccgaggatgtgtacatcgtcaagaacaagcca gtgctgcttgtgtgcaaggccgtgcccgccacgcagatcttcttcaagtgcaacggggag tgggtgcgccaggtggaccacgtgatcgagcgcagcacagacgggagcagtgggctgccc accatggaggtccgcattaatgtctcaaggcagcaggtcgagaaggtgttcgggctggag gaatactggtgccagtgcgtggcatggagctcctcgggcaccaccaagagtcagaaggcc tacatccgcatagcctatttgcgcaagaacttcgagcaggagccgctggccaaggaggtg tccctggagcagggcatcgtgctgccctgccgtccaccggagggcatccctccagccgag gtggagtggctccggaacgaggacctggtggacccgtccctggaccccaatgtatacatc acgcgggagcacagcctggtggtgcgacaggcccgccttgctgacacggccaactacacc tgcgtggccaagaacatcgtggcacgtcgccgcagcgcctccgctgctgtcatcgtctac gtggacggcagctggagcccgtggagcaagtggtcggcctgtgggctggactgcacccac tggcggagccgtgagtgctctgacccagcaccccgcaacggaggggaggagtgccagggc actgacctggacacccgcaactgtaccagtgacctctgtgtacacactgcttctggccct gaggacgtggccctctatgtgggcctcatcgccgtggccgtctgcctggtcctgctgctg cttgtcctcatcctcgtttattgccggaagaaggaggggctggactcagatgtggctgac tcgtccattctcacctcaggcttccagcccgtcagcatcaagcccagcaaagcagacaac ccccatctgctcaccatccagccggacctcagcaccaccaccaccacctaccagggcagt ctctgtccccggcaggatgggcccagccccaagttccagctcaccaatgggcacctgctc agccccctgggtggcggccgccacacactgcaccacagctctcccacctctgaggccgag gagttcgtctcccgcctctccacccagaactacttccgctccctgccccgaggcaccagc aacatgacctatgggaccttcaacttcctcgggggccggctgatgatccctaatacagga atcagcctcctcatccccccagatgccataccccgagggaagatctatgagatctacctc acgctgcacaagccggaagacgtgaggttgcccctagctggctgtcagaccctgctgagt cccatcgttagctgtggaccccctggcgtcctgctcacccggccagtcatcctggctatg gaccactgtggggagcccagccctgacagctggagcctgcgcctcaaaaagcagtcgtgc gagggcagctgggaggatgtgctgcacctgggcgaggaggcgccctcccacctctactac tgccagctggaggccagtgcctgctacgtcttcaccgagcagctgggccgctttgccctg gtgggagaggccctcagcgtggctgccgccaagcgcctcaagctgcttctgtttgcgccg gtggcctgcacctccctcgagtacaacatccgggtctactgcctgcatgacacccacgat gcactcaaggaggtggtgcagctggagaagcagctggggggacagctgatccaggagcca cgggtcctgcacttcaaggacagttaccacaacctgcgcctatccatccacgatgtgccc agctccctgtggaagagtaagctccttgtcagctaccaggagatccccttttatcacatc tggaatggcacgcagcggtacttgcactgcaccttcaccctggagcgtgtcagccccagc actagtgacctggcctgcaagctgtgggtgtggcaggtggagggcgacgggcagagcttc agcatcaacttcaacatcaccaaggacacaaggtttgctgagctgctggctctggagagt gaagcgggggtcccagccctggtgggccccagtgccttcaagatccccttcctcattcgg cagaagataatttccagcctggacccaccctgtaggcggggtgccgactggcggactctg gcccagaaactccacctggacagccatctcagcttctttgcctccaagcccagccccaca gccatgatcctcaacctgtgggaggcgcggcacttccccaacggcaacctcagccagctg gctgcagcagtggctggactgggccagccagacgctggcctcttcacagtgtcggaggct gagtgctga |
Protein Sequence |
>90249 : length: 842 MAVRPGLWPALLGIVLAAWLRGSGAQQSATVANPVPGANPDLLPHFLVEPEDVYIVKNKP VLLVCKAVPATQIFFKCNGEWVRQVDHVIERSTDGSSGLPTMEVRINVSRQQVEKVFGLE EYWCQCVAWSSSGTTKSQKAYIRIAYLRKNFEQEPLAKEVSLEQGIVLPCRPPEGIPPAE VEWLRNEDLVDPSLDPNVYITREHSLVVRQARLADTANYTCVAKNIVARRRSASAAVIVY VDGSWSPWSKWSACGLDCTHWRSRECSDPAPRNGGEECQGTDLDTRNCTSDLCVHTASGP EDVALYVGLIAVAVCLVLLLLVLILVYCRKKEGLDSDVADSSILTSGFQPVSIKPSKADN PHLLTIQPDLSTTTTTYQGSLCPRQDGPSPKFQLTNGHLLSPLGGGRHTLHHSSPTSEAE EFVSRLSTQNYFRSLPRGTSNMTYGTFNFLGGRLMIPNTGISLLIPPDAIPRGKIYEIYL TLHKPEDVRLPLAGCQTLLSPIVSCGPPGVLLTRPVILAMDHCGEPSPDSWSLRLKKQSC EGSWEDVLHLGEEAPSHLYYCQLEASACYVFTEQLGRFALVGEALSVAAAKRLKLLLFAP VACTSLEYNIRVYCLHDTHDALKEVVQLEKQLGGQLIQEPRVLHFKDSYHNLRLSIHDVP SSLWKSKLLVSYQEIPFYHIWNGTQRYLHCTFTLERVSPSTSDLACKLWVWQVEGDGQSF SINFNITKDTRFAELLALESEAGVPALVGPSAFKIPFLIRQKIISSLDPPCRRGADWRTL AQKLHLDSHLSFFASKPSPTAMILNLWEARHFPNGNLSQLAAAVAGLGQPDAGLFTVSEA EC |