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| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 841 |
Name | CASP8 |
Synonymous | ALPS2B|CAP4|Casp-8|FLICE|MACH|MCH5;caspase 8, apoptosis-related cysteine peptidase;CASP8;caspase 8, apoptosis-related cysteine peptidase |
Definition | FADD-homologous ICE/CED-3-like protease|FADD-like ICE|ICE-like apoptotic protease 5|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|MORT1-associated ced-3 homolog|apoptotic cysteine protease|apoptotic protease Mch-5|caspase 8, apoptosis-related cystein |
Position | 2q33-q34 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
interacts with |
MAP3K14 | BIOGRID; PUBMED:11002417; |
interacts with |
MAPK8 | BIOGRID; PUBMED:15659383; |
interacts with |
MSN | BIOGRID; PUBMED:15659383; |
interacts with |
TRADD | BIOGRID; PUBMED:12887920; |
interacts with |
TNFRSF10A | BIOGRID; PUBMED:9325248; |
interacts with |
TRAF2 | BIOGRID; PUBMED:12887920; |
interacts with |
TRAF2 | BIOGRID; PUBMED:21282461; |
interacts with |
FASLG | BIOGRID; PUBMED:12753742; |
interacts with |
FASLG | BIOGRID; PUBMED:12887920; |
interacts with |
FASLG | BIOGRID; PUBMED:15659383; |
interacts with |
TNFRSF1A | BIOGRID; PUBMED:15659383; |
interacts with |
TNFAIP3 | BIOGRID; PUBMED:19060883; |
interacts with |
TNFRSF10B | BIOGRID; PUBMED:11940602; |
interacts with |
TNFRSF10B | BIOGRID; PUBMED:15659383; |
interacts with |
TNFRSF10B | BIOGRID; PUBMED:9325248; |
interacts with |
FAS | BIOGRID; PUBMED:15659383; |
interacts with |
FAS | BIOGRID; PUBMED:9208847; |
interacts with |
FAS | BIOGRID; PUBMED:9325248; |
interacts with |
TRAF1 | BIOGRID; PUBMED:11098060; |
interacts with |
TRAF1 | BIOGRID; PUBMED:12887920; |
interacts with |
TFCP2 | BIOGRID; PUBMED:16169070; |
interacts with |
CFLAR | BIOGRID; PUBMED:11741985; |
interacts with |
CFLAR | BIOGRID; PUBMED:12215447; |
interacts with |
CFLAR | BIOGRID; PUBMED:12887920; |
interacts with |
CFLAR | BIOGRID; PUBMED:9208847; |
interacts with |
CFLAR | BIOGRID; PUBMED:9228018; |
interacts with |
CFLAR | BIOGRID; PUBMED:9289491; |
interacts with |
CFLAR | BIOGRID; PUBMED:9326610; |
interacts with |
CASP14 | BIOGRID; PUBMED:9792675; |
interacts with |
NOD1 | BIOGRID; PUBMED:10329646; |
interacts with |
NLRC4 | BIOGRID; PUBMED:20085538; |
interacts with |
NOL3 | BIOGRID; PUBMED:9560245; |
interacts with |
NR1H4 | BIOGRID; PUBMED:11733517; |
interacts with |
CASP4 | BIOGRID; PUBMED:8962078; |
interacts with |
CASP1 | BIOGRID; PUBMED:8962078; |
interacts with |
BIRC2 | BIOGRID; PUBMED:12887920; |
interacts with |
BID | BIOGRID; PUBMED:11832478; |
interacts with |
BID | BIOGRID; PUBMED:15659383; |
interacts with |
BCAP31 | BIOGRID; PUBMED:9334338; |
interacts with |
CASP8AP2 | BIOGRID; PUBMED:10235259; |
interacts with |
BCL2 | BIOGRID; PUBMED:11406564; |
interacts with |
EZR | BIOGRID; PUBMED:15659383; |
interacts with |
RALGDS | BIOGRID; PUBMED:21525013; |
interacts with |
HIP1 | BIOGRID; PUBMED:11788820; |
interacts with |
HDAC7 | BIOGRID; PUBMED:18458084; |
interacts with |
FADD | BIOGRID; PUBMED:12107169; |
interacts with |
FADD | BIOGRID; PUBMED:12887920; |
interacts with |
FADD | BIOGRID; PUBMED:12911633; |
interacts with |
FADD | BIOGRID; PUBMED:15659383; |
interacts with |
FADD | BIOGRID; PUBMED:19060883; |
interacts with |
FADD | BIOGRID; PUBMED:21525013; |
interacts with |
FADD | BIOGRID; PUBMED:8681376; |
interacts with |
FADD | BIOGRID; PUBMED:9228018; |
interacts with |
FAF1 | BIOGRID; PUBMED:21282461; |
interacts with |
ARHGDIA | BIOGRID; PUBMED:15659383; |
interacts with |
CASP7 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP7 | BIOGRID; PUBMED:8962078; |
interacts with |
CASP10 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP10 | BIOGRID; PUBMED:12887920; |
interacts with |
CASP10 | BIOGRID; PUBMED:15659383; |
interacts with |
CASP10 | BIOGRID; PUBMED:8962078; |
interacts with |
CASP6 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP6 | BIOGRID; PUBMED:12232792; |
interacts with |
CASP6 | BIOGRID; PUBMED:8962078; |
interacts with |
CASP3 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP3 | BIOGRID; PUBMED:8962078; |
interacts with |
CASP9 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP9 | BIOGRID; PUBMED:8962078; |
interacts with |
DEDD2 | BIOGRID; PUBMED:11965497; |
interacts with |
DEDD2 | BIOGRID; PUBMED:12527898; |
interacts with |
DEDD | BIOGRID; PUBMED:11965497; |
interacts with |
DEDD | BIOGRID; PUBMED:12527898; |
interacts with |
DEDD | BIOGRID; PUBMED:9774341; |
interacts with |
IKBKB | BIOGRID; PUBMED:11002417; |
interacts with |
CHUK | BIOGRID; PUBMED:11002417; |
interacts with |
RALBP1 | BIOGRID; PUBMED:12887920; |
interacts with |
RIPK1 | BIOGRID; PUBMED:11002417; |
interacts with |
RIPK1 | BIOGRID; PUBMED:18570872; |
interacts with |
RIPK1 | BIOGRID; PUBMED:19060883; |
interacts with |
RIPK1 | BIOGRID; PUBMED:21282461; |
interacts with |
RHOA | BIOGRID; PUBMED:15659383; |
interacts with |
APAF1 | BIOGRID; PUBMED:9539746; |
interacts with |
IFT57 | BIOGRID; PUBMED:11788820; |
interacts with |
CASP2 | BIOGRID; PUBMED:11832478; |
interacts with |
CASP2 | BIOGRID; PUBMED:8962078; |
interacts with |
PEA15 | BIOGRID; PUBMED:10442631; |
interacts with |
PEA15 | BIOGRID; PUBMED:10493725; |
interacts with |
VIM | BIOGRID; PUBMED:16169070; |
interacts with |
CHD3 | BIOGRID; PUBMED:16169070; |
interacts with |
TRADD | CELL_MAP; PUBMED:12887920; |
interacts with |
TRAF2 | CELL_MAP; PUBMED:12887920; |
interacts with |
FADD | CELL_MAP; PUBMED:12887920; |
interacts with |
CASP10 | CELL_MAP; PUBMED:12887920; |
interacts with |
RIPK1 | CELL_MAP; PUBMED:12887920; |
interacts with |
MAPK1 | HPRD; PUBMED:17290218; |
interacts with |
MAP3K14 | HPRD; PUBMED:11002417; |
interacts with |
MAPK3 | HPRD; PUBMED:17290218; |
interacts with |
MAP4K4 | HPRD; PUBMED:11002417; |
interacts with |
TRADD | HPRD; PUBMED:12887920; |
interacts with |
TNFRSF10A | HPRD; PUBMED:10894160; |
interacts with |
TNFRSF10A | HPRD; PUBMED:12218097; |
interacts with |
TNFRSF10A | HPRD; PUBMED:9325248; |
interacts with |
TRAF2 | HPRD; PUBMED:12887920; |
interacts with |
TRAF2 | HPRD; PUBMED:16227629; |
interacts with |
TNFRSF1A | HPRD; PUBMED:12887920; |
interacts with |
EDA2R | HPRD; PUBMED:15280356; |
interacts with |
MAPT | HPRD; PUBMED:12888622; |
interacts with |
TNFRSF10B | HPRD; PUBMED:10894160; |
interacts with |
TNFRSF10B | HPRD; PUBMED:12218097; |
interacts with |
TNFRSF10B | HPRD; PUBMED:9325248; |
interacts with |
TOPORS | HPRD; PUBMED:17290218; |
interacts with |
TRAF1 | HPRD; PUBMED:11098060; |
interacts with |
TFCP2 | HPRD; PUBMED:16169070; |
interacts with |
CFLAR | HPRD; PUBMED:9289491; |
interacts with |
CFLAR | HPRD; PUBMED:9325248; |
interacts with |
CASP14 | HPRD; PUBMED:9792675; |
interacts with |
NOD1 | HPRD; PUBMED:10329646; |
interacts with |
NLRC4 | HPRD; PUBMED:12646168; |
interacts with |
NOL3 | HPRD; PUBMED:9560245; |
interacts with |
NR1H4 | HPRD; PUBMED:11733517; |
interacts with |
PRKCZ | HPRD; PUBMED:11016947; |
interacts with |
KRR1 | HPRD; PUBMED:12887920; |
interacts with |
BIRC2 | HPRD; PUBMED:12887920; |
interacts with |
PYCARD | HPRD; PUBMED:12646168; |
interacts with |
BCL2L1 | HPRD; PUBMED:11733517; |
interacts with |
BFAR | HPRD; PUBMED:10716992; |
interacts with |
BCAP31 | HPRD; PUBMED:9334338; |
interacts with |
CASP8AP2 | HPRD; PUBMED:11340079; |
interacts with |
CASP8AP2 | HPRD; PUBMED:17245429; |
interacts with |
BCL2 | HPRD; PUBMED:11406564; |
interacts with |
HIP1 | HPRD; PUBMED:11788820; |
interacts with |
EIF2AK2 | HPRD; PUBMED:11555640; |
interacts with |
GMEB1 | HPRD; PUBMED:16497673; |
interacts with |
FADD | HPRD; PUBMED:10894160; |
interacts with |
FADD | HPRD; PUBMED:12107169; |
interacts with |
FADD | HPRD; PUBMED:12198154; |
interacts with |
FADD | HPRD; PUBMED:12887920; |
interacts with |
FAF1 | HPRD; PUBMED:12702723; |
interacts with |
FYN | HPRD; PUBMED:10435619; |
interacts with |
CDKN1B | HPRD; PUBMED:11420686; |
interacts with |
CDK11A | HPRD; PUBMED:9632733; |
interacts with |
CASP10 | HPRD; PUBMED:11717445; |
interacts with |
CASP10 | HPRD; PUBMED:12198154; |
interacts with |
CASP10 | HPRD; PUBMED:9325248; |
interacts with |
CASP6 | HPRD; PUBMED:12232792; |
interacts with |
CASP3 | HPRD; PUBMED:11437602; |
interacts with |
CDH1 | HPRD; PUBMED:12189238; |
interacts with |
CTNNB1 | HPRD; PUBMED:12189238; |
interacts with |
CRADD | HPRD; PUBMED:11002417; |
interacts with |
DEDD2 | HPRD; PUBMED:12527898; |
interacts with |
DEDD | HPRD; PUBMED:12527898; |
interacts with |
CDK11B | HPRD; PUBMED:9632733; |
interacts with |
IKBKB | HPRD; PUBMED:11002417; |
interacts with |
ILK | HPRD; PUBMED:16936772; |
interacts with |
CHUK | HPRD; PUBMED:11002417; |
interacts with |
RALBP1 | HPRD; PUBMED:16227629; |
interacts with |
RB1 | HPRD; PUBMED:15735701; |
interacts with |
RIPK1 | HPRD; PUBMED:11002417; |
interacts with |
RIPK2 | HPRD; PUBMED:9575181; |
interacts with |
AR | HPRD; PUBMED:17170703; |
interacts with |
APAF1 | HPRD; PUBMED:9539746; |
interacts with |
IFT57 | HPRD; PUBMED:11788820; |
interacts with |
KRT18 | HPRD; PUBMED:10891503; |
interacts with |
PEA15 | HPRD; PUBMED:10493725; |
interacts with |
PICALM | HPRD; PUBMED:10926122; |
interacts with |
PARK2 | HPRD; PUBMED:12692130; |
interacts with |
PLEC | HPRD; PUBMED:10891503; |
interacts with |
PIAS1 | HPRD; PUBMED:15782135; |
interacts with |
PSEN1 | HPRD; PUBMED:10069390; |
interacts with |
PSEN2 | HPRD; PUBMED:9990034; |
interacts with |
STK24 | HPRD; PUBMED:12107159; |
interacts with |
SRF | HPRD; PUBMED:11387340; |
interacts with |
VIM | HPRD; PUBMED:11423904; |
interacts with |
USO1 | HPRD; PUBMED:12438416; |
interacts with |
RYBP | HPRD; PUBMED:11395500; |
interacts with |
PARP2 | HPRD; PUBMED:12065591; |
interacts with |
PCYT1A | HPRD; PUBMED:12052891; |
interacts with |
BCAP31 | INTACT; PUBMED:21183955; |
interacts with |
FIS1 | INTACT; PUBMED:21183955; |
interacts with |
FADD | INTACT; PUBMED:21458669; |
interacts with |
FADD | INTACT; PUBMED:21525013; |
interacts with |
RIPK1 | INTACT; PUBMED:21458669; |
interacts with |
RIPK1 | INTACT; PUBMED:21525013; |
interacts with |
MAPK1 | MINT; PUBMED:17290218; |
interacts with |
MAPK3 | MINT; PUBMED:17290218; |
interacts with |
FASLG | MINT; PUBMED:16498403; |
interacts with |
TOPORS | MINT; PUBMED:17290218; |
interacts with |
FAS | MINT; PUBMED:16498403; |
interacts with |
FAS | MINT; PUBMED:17159907; |
interacts with |
TFCP2 | MINT; PUBMED:16169070; |
interacts with |
NCL | MINT; PUBMED:17290218; |
interacts with |
NUCB2 | MINT; PUBMED:18154733; |
interacts with |
NUCB1 | MINT; PUBMED:18154733; |
interacts with |
CASP8AP2 | MINT; PUBMED:17245429; |
interacts with |
FADD | MINT; PUBMED:17159907; |
interacts with |
CASP10 | MINT; PUBMED:17159907; |
interacts with |
Casp8 | MINT; PUBMED:17170703; |
interacts with |
AR | MINT; PUBMED:17170703; |
interacts with |
VIM | MINT; PUBMED:16169070; |
interacts with |
CHD3 | MINT; PUBMED:16169070; |
Metabolic Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
metabolic catalysis |
MAVS | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
metabolic catalysis |
FADD | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
metabolic catalysis |
RIPK1 | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
Signaling Interaction | | Top | |
|
Interaction Type |
Interactor |
Data Source |
|---|---|---|
reacts with |
CFLAR | IMID; PUBMED:9217161; |
reacts with |
BCAP31 | IMID; PUBMED:9334338; |
reacts with |
FADD | IMID; PUBMED:8681377; |
reacts with |
CASP8 | IMID; PUBMED:11042212; |
reacts with |
CASP8 | IMID; PUBMED:8681377; |
reacts with |
CASP8 | IMID; PUBMED:9217161; |
reacts with |
CASP8 | IMID; PUBMED:9334338; |
reacts with |
MAP3K5 | NCI_NATURE; PUBMED:9740801; |
state change |
MADD | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
state change |
TRADD | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
TRADD | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
state change |
TNFRSF10A | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
TNFRSF10A | NCI_NATURE; PUBMED:16940186;PUBMED:11278665;PUBMED:11376335;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:10783243; |
state change |
TNFSF10 | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
TNFSF10 | NCI_NATURE; PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
TNFSF10 | NCI_NATURE; PUBMED:16940186;PUBMED:11278665;PUBMED:11376335;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:10783243; |
state change |
TRAF2 | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
TRAF2 | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
reacts with |
FASLG | NCI_NATURE; PUBMED:12110583;PUBMED:11279218; |
reacts with |
FASLG | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
FASLG | NCI_NATURE; PUBMED:20038679;PUBMED:8681377;PUBMED:10894163;PUBMED:12110583;PUBMED:9184224;PUBMED:11279218;PUBMED:11739735; |
reacts with |
FASLG | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
FASLG | NCI_NATURE; PUBMED:9740801; |
state change |
FASLG | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
state change |
FASLG | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
state change |
TNFRSF1A | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
TNFRSF1A | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
state change |
TNF | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
TNF | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
state change |
TNFRSF10B | NCI_NATURE; PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
reacts with |
FAS | NCI_NATURE; PUBMED:12110583;PUBMED:11279218; |
reacts with |
FAS | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
FAS | NCI_NATURE; PUBMED:20038679;PUBMED:8681377;PUBMED:10894163;PUBMED:12110583;PUBMED:9184224;PUBMED:11279218;PUBMED:11739735; |
reacts with |
FAS | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
FAS | NCI_NATURE; PUBMED:9740801; |
state change |
FAS | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
state change |
FAS | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
CFLAR | NCI_NATURE; PUBMED:20038679;PUBMED:8681377;PUBMED:10894163;PUBMED:12110583;PUBMED:9184224;PUBMED:11279218;PUBMED:11739735; |
state change |
CFLAR | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
CFLAR | NCI_NATURE; PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
BIRC2 | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
BIRC3 | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
BIRC3 | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
state change |
EZR | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
FADD | NCI_NATURE; PUBMED:12110583;PUBMED:11279218; |
reacts with |
FADD | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
FADD | NCI_NATURE; PUBMED:20038679;PUBMED:8681377;PUBMED:10894163;PUBMED:12110583;PUBMED:9184224;PUBMED:11279218;PUBMED:11739735; |
reacts with |
FADD | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
reacts with |
FADD | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
reacts with |
FADD | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
FADD | NCI_NATURE; PUBMED:9740801; |
state change |
FADD | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
FADD | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
FADD | NCI_NATURE; PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
FADD | NCI_NATURE; PUBMED:16940186;PUBMED:11278665;PUBMED:11376335;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:10783243; |
state change |
FADD | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
state change |
FADD | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:12110583;PUBMED:11279218; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:16940186;PUBMED:11278665;PUBMED:11376335;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:10783243; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:20038679;PUBMED:8681377;PUBMED:10894163;PUBMED:12110583;PUBMED:9184224;PUBMED:11279218;PUBMED:11739735; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
CASP8 | NCI_NATURE; PUBMED:9740801; |
state change |
CASP8 | NCI_NATURE; PUBMED:9184224;PUBMED:11739735;PUBMED:16619028; |
state change |
CASP8 | NCI_NATURE; PUBMED:9501089;PUBMED:18635548;PUBMED:16619028; |
reacts with |
DAXX | NCI_NATURE; PUBMED:9740801; |
state change |
CRADD | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
reacts with |
ITGB3 | NCI_NATURE; PUBMED:11684710; |
state change |
RIPK1 | NCI_NATURE; PUBMED:15357952;PUBMED:8681376;PUBMED:17024246; |
state change |
RIPK1 | NCI_NATURE; PUBMED:8681377;PUBMED:8681376; |
reacts with |
ITGAV | NCI_NATURE; PUBMED:11684710; |
state change |
DAP3 | NCI_NATURE; PUBMED:11376335;PUBMED:16940186;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:15105837;PUBMED:10783243; |
state change |
DAP3 | NCI_NATURE; PUBMED:16940186;PUBMED:11278665;PUBMED:11376335;PUBMED:10894160;PUBMED:10894161;PUBMED:9311998;PUBMED:10783243; |
state change |
CLTC | NCI_NATURE; PUBMED:16498403;PUBMED:12832037;PUBMED:18635548;PUBMED:11739735; |
reacts with |
MAVS | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
reacts with |
TRADD | REACTOME; PUBMED:12887920; |
reacts with |
TNFSF10 | REACTOME; PUBMED:10894160; |
reacts with |
TRAF2 | REACTOME; PUBMED:12887920; |
reacts with |
FASLG | REACTOME; PUBMED:8681376; |
reacts with |
FASLG | REACTOME; PUBMED:9721089; |
reacts with |
TNFRSF10B | REACTOME; PUBMED:10894160; |
reacts with |
FAS | REACTOME; PUBMED:8681376; |
reacts with |
FAS | REACTOME; PUBMED:9721089; |
reacts with |
FADD | REACTOME; PUBMED:10894160; |
reacts with |
FADD | REACTOME; PUBMED:12887920; |
reacts with |
FADD | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
reacts with |
FADD | REACTOME; PUBMED:8681376; |
reacts with |
FADD | REACTOME; PUBMED:9721089; |
reacts with |
CASP8 | REACTOME; PUBMED:10894160; |
reacts with |
CASP8 | REACTOME; PUBMED:12887920; |
reacts with |
CASP8 | REACTOME; PUBMED:15254227; |
reacts with |
CASP8 | REACTOME; PUBMED:8681376; |
reacts with |
CASP8 | REACTOME; PUBMED:9721089; |
reacts with |
CASP10 | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |
reacts with |
RIPK1 | REACTOME; PUBMED:12887920; |
reacts with |
RIPK1 | REACTOME; PUBMED:16618810;PUBMED:18761323;PUBMED:16585540;PUBMED:12884866;PUBMED:11717445; |