Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

55615

Name

PRR5

Synonymous

FLJ20185k|PP610|PROTOR-1|PROTOR1;proline rich 5 (renal);PRR5;proline rich 5 (renal)

Definition

proline-rich protein 5|protein observed with Rictor-1

Position

22q13

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors

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Regulation From TransFac database

mTOR(h) + Protor-1-isoform1(h) <==> mTOR(h):Protor-1-isoform1(h) (binding)
Protor-1-isoform1(h) + rictor(h) <==> Protor-1-isoform1(h):rictor(h) (binding)
PRR5(h) --> Protor-1-isoform1(h) (expression).
Protor-1(h) + mTOR(h) <==> Protor-1(h):mTOR(h) (binding)
mTOR(h) + Protor-1(h) + rictor(h) <==> mTOR(h):Protor-1(h):rictor(h) (binding)
Protor-1(h) + mTOR(h) + rictor(m.s.) <==> Protor-1(h):mTOR(h):rictor(m.s.) (binding)
Protor-1(h) + rictor(h) <==> Protor-1(h):rictor(h) (binding)
Protor-1(h) + rictor(m.s.) <==> Protor-1(h):rictor(m.s.) (binding)
Protor-1(h) --> p70S6K1(h){pT389} (increase of phosphorylation)
Protor-1(h) --> 4E-BP1(h){pT} (increase of phosphorylation)
Protor-1(h) --> PDGFRbeta(h) (increase of abundance)
Protor-1(h) --> PDGFRB(h) (transactivation)
mTOR(h) + rictor(h) + mLST8(h) + SIN1(h) + Protor-1(h) <==> mTOR(h):rictor(h):mLST8(h):SIN1(h):Protor-1(h) (binding)
PRR5(h) --> Protor-1(h) (expression).
PRR5(h) --> Protor-1-isoform2(h) (expression).
Protor-1-isoform3(h) + mTOR(h) <==> Protor-1-isoform3(h):mTOR(h) (binding)
Protor-1-isoform3(h) + rictor(h) <==> rictor(h):Protor-1-isoform3(h) (binding)
PRR5(h) --> Protor-1-isoform3(h) (expression).
PRR5(h) --> Protor-1-isoform4(h) (expression).

Post Transcriptional Modification From dbPTM

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There is no record for PRR5

Methylation Profile From DiseaseMeth database

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Chromosome

Location

Source

chr22

Promoter: 43441757 - 43443757Agilent_014791

chr22

Promoter: 43449852 - 43451852Agilent_014791

chr22

Promoter: 43475247 - 43477247Agilent_014791

chr22

Promoter: 43441757 - 43443757GSE27584

chr22

Promoter: 43441757 - 43443757GSE27584

chr22

Promoter: 43449852 - 43451852GSE27584

chr22

Promoter: 43449852 - 43451852GSE27584

chr22

Promoter: 43475247 - 43477247GSE27584

chr22

Promoter: 43475247 - 43477247Agilent_014791_44K

chr22

Promoter: 43441757 - 43443757Agilent_014791

chr22

Promoter: 43475247 - 43477247Agilent_014791


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