| Gene Information |
| Gene ID: | | 10019 |
| Symbol: | | SH2B3 |
| Full Name: | | SH2B adaptor protein 3 |
| Alias: | | LNK |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 12 |
| Genetic Location: | | 12q24 |
| Physical Location: | | 110328134-110373809 on NC_000012.10 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | H77460 | | Fold Change: | | 1.67 | | P Value: | | 6.00E-03 | | Tissue: | | Nucleus accumbens |
| | Dataset Information | | Name: | | 15816859 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex and nucleus accumbens | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed | | Summary: | | Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0004871 | signal transducer activity | Molecular Function | IEA | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0007242 | intracellular signaling cascade | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 10019 |
| HGNC: | | 29605 |
| Ensembl: | | ENSG00000111252 |
| MIM: | | 605093 |
| HPRD: | | 05480 |
| HuGE Navigator: | | 10019 |
| dbSNP: | | SH2B3 |
| GeneCard: | | SH2B3 |
| AceView: | | SH2B3 |
