ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CTDSP2

Full Name:

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

Alias:

OS4|PSR2|SCP2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

12q13-q15

Physical Location:

56499976-56527013 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AF022231
Fold Change:		-1.6, -1.5
Note:		Differential Expression on the cDNA array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005730.3	NP_005721.3	NC_000012.10 range: 56499976..56527013, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005575	cellular_component	Cellular Component	ND
GO:0005625	soluble fraction	Cellular Component	TAS (9315096)
GO:0005634	nucleus	Cellular Component	IEA
GO:0003674	molecular_function	Molecular Function	ND
GO:0004721	phosphoprotein phosphatase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0016791	phosphoric monoester hydrolase activity	Molecular Function	IEA
GO:0008150	biological_process	Biological Process	ND