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Gene Information
Gene ID:101214
Full Name:transformer 2 alpha homolog (Drosophila)
Organism:Mus musculus (Mouse)
Genetic Location:6 B2.3
Physical Location:49193919-49214050 on NC_000072.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 29896    Symbol (Name): TRA2A (-)
Ortholog Status:The human GeneID 29896 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI841448
Fold Change:-1.5, -1.5, -1.4, -1
Note:4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2
Dataset Information
Tissue:Whole brain
Phenotype:Acute ethanol response
Publication:Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.
Gene Information
Original ID1:1500010G04Rik
Dataset Information
Tissue:Whole brain
Phenotype:Alcohol preference
Publication:Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_198102.2NP_932770.2NC_000072.5 range: 49193919..49214050, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (11401487)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0003723RNA bindingMolecular FunctionISS (11401487)
GO:0042802identical protein bindingMolecular FunctionIPI (16249178)
GO:0006397mRNA processingBiological ProcessIEA
GO:0008150biological_processBiological ProcessND
GO:0008380RNA splicingBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:101214