| Gene Information |
| Gene ID: | | 101214 |
| Symbol: | | Tra2a |
| Full Name: | | transformer 2 alpha homolog (Drosophila) |
| Alias: | | 1500010G04Rik|AL022798|G430041M01Rik|mAWMS1 |
| Organism: | | Mus musculus (Mouse) |
| Chromosome: | | 6 |
| Genetic Location: | | 6 B2.3 |
| Physical Location: | | 49193919-49214050 on NC_000072.5, complement |
| Gene Type: | | protein-coding |
| Human Ortholog: | | GeneID: 29896 Symbol (Name): TRA2A (-) |
| Ortholog Status: | | The human GeneID 29896 is not in current human dataset. |
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| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | AI841448 | | Fold Change: | | -1.5, -1.5, -1.4, -1 | | Note: | | 4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2 |
| | Dataset Information | | Name: | | 15002731 | | Method: | | Microarray | | Tissue: | | Whole brain | | Phenotype: | | Acute ethanol response | | Publication: | | Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed | | Summary: | | We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain. |
| | Gene Information | | Original ID1: | | 1500010G04Rik |
| | Dataset Information | | Name: | | 16618939 | | Method: | | Microarray | | Tissue: | | Whole brain | | Phenotype: | | Alcohol preference | | Publication: | | Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed | | Summary: | | Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005634 | nucleus | Cellular Component | IDA (11401487) | |
| GO:0000166 | nucleotide binding | Molecular Function | IEA | |
| GO:0003676 | nucleic acid binding | Molecular Function | IEA | |
| GO:0003723 | RNA binding | Molecular Function | ISS (11401487) | |
| GO:0042802 | identical protein binding | Molecular Function | IPI (16249178) | |
| GO:0006397 | mRNA processing | Biological Process | IEA | |
| GO:0008150 | biological_process | Biological Process | ND | |
| GO:0008380 | RNA splicing | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 101214 |
| MGI: | |
| Ensembl: | | ENSMUSG00000029817 |
| dbSNP: | | Tra2a |
| AceView: | | Tra2a |
