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Gene Information
Gene ID:1016
Symbol:CDH18
Full Name:cadherin 18, type 2
Alias:CDH14|CDH14L|CDH24|EY-CADHERIN
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5p15.2-p15.1
Physical Location:19508897-20017045 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U59325
Fold Change:1.4, 1.7
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004934.2NP_004925.1NC_000005.8 range: 19508897..20017045, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0007155cell adhesionBiological ProcessIEA
GO:0007156homophilic cell adhesionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:1016
HGNC:1757
Ensembl:ENSG00000145526
MIM:603019
HPRD:04314
HuGE Navigator:1016
dbSNP:CDH18
GeneCard:CDH18
AceView:CDH18