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Gene Information
Gene ID:1017
Symbol:CDK2
Full Name:cyclin-dependent kinase 2
Alias:p33(CDK2)
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12q13
Physical Location:54646825-54652834 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CDK2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001798.3NP_001789.2NC_000012.10 range: 54646825..54652834
NM_052827.2NP_439892.2NC_000012.10 range: 54646825..54652834
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005829cytosolCellular ComponentEXP (1312467|7799941|9840943|11907280)
GO:0005737cytoplasmCellular ComponentTAS (10767298)
GO:0005654nucleoplasmCellular ComponentEXP (1396589|7629134|9840943|10323868|10339564|10454565|10548110|11231585|11340163|11907280|11931757|1522)
GO:0005634nucleusCellular ComponentIDA (16109376)
GO:0000307cyclin-dependent protein kinase holoenzyme complexCellular ComponentIDA (8692841)
GO:0004693cyclin-dependent protein kinase activityMolecular FunctionEXP (10548110)
GO:0016740transferase activityMolecular FunctionIEA
GO:0035173histone kinase activityMolecular FunctionIDA (8692841)
GO:0042802identical protein bindingMolecular FunctionIPI (17353931)
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0004674protein serine/threonine kinase activityMolecular FunctionIEA
GO:0005524ATP bindingMolecular FunctionIEA
GO:0004693cyclin-dependent protein kinase activityMolecular FunctionTAS (1653904)
GO:0008284positive regulation of cell proliferationBiological ProcessTAS (10767298)
GO:0007089traversing start control point of mitotic cell cycleBiological ProcessTAS (9933170)
GO:0007067mitosisBiological ProcessIEA
GO:0007049cell cycleBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0006275regulation of DNA replicationBiological ProcessTAS (9933170)
GO:0000086G2/M transition of mitotic cell cycleBiological ProcessTAS (1653904)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:1017
HGNC:1771
Ensembl:ENSG00000123374
MIM:116953
HPRD:00310
HuGE Navigator:1017
dbSNP:CDK2
GeneCard:CDK2
AceView:CDK2