| Gene Information |
| Gene ID: | | 1019 |
| Symbol: | | CDK4 |
| Full Name: | | cyclin-dependent kinase 4 |
| Alias: | | CMM3|MGC14458|PSK-J3 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 12 |
| Genetic Location: | | 12q14 |
| Physical Location: | | 56428269-56432430 on NC_000012.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005654 | nucleoplasm | Cellular Component | EXP (9190208|16782892) | |
| GO:0000307 | cyclin-dependent protein kinase holoenzyme complex | Cellular Component | IDA (17420273) | |
| GO:0005829 | cytosol | Cellular Component | EXP (9106657) | |
| GO:0005634 | nucleus | Cellular Component | IDA (16109376) | |
| GO:0016740 | transferase activity | Molecular Function | IEA | |
| GO:0005524 | ATP binding | Molecular Function | IEA | |
| GO:0005515 | protein binding | Molecular Function | IPI (9106657|11896535|15232106|15558030|16169070|17274640|17353931|17909018) | |
| GO:0004693 | cyclin-dependent protein kinase activity | Molecular Function | IEA | |
| GO:0004672 | protein kinase activity | Molecular Function | IEA | |
| GO:0000166 | nucleotide binding | Molecular Function | IEA | |
| GO:0048146 | positive regulation of fibroblast proliferation | Biological Process | IMP (17420273) | |
| GO:0010468 | regulation of gene expression | Biological Process | IMP (17420273) | |
| GO:0007049 | cell cycle | Biological Process | IEA | |
| GO:0006468 | protein amino acid phosphorylation | Biological Process | IEA | |
| GO:0000082 | G1/S transition of mitotic cell cycle | Biological Process | IMP (7603984) | |
| GO:0051301 | cell division | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 1019 |
| HGNC: | | 1773 |
| Ensembl: | | ENSG00000135446 |
| MIM: | | 123829 |
| HPRD: | | 00447 |
| HuGE Navigator: | | 1019 |
| dbSNP: | | CDK4 |
| GeneCard: | | CDK4 |
| AceView: | | CDK4 |
