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Gene Information
Gene ID:1021
Symbol:CDK6
Full Name:cyclin-dependent kinase 6
Alias:MGC59692|PLSTIRE
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7q21-q22
Physical Location:92072170-92301147 on NC_000007.12, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CDK6
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001259.5NP_001250.1NC_000007.12 range: 92072170..92301147, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (14985467)
GO:0000307cyclin-dependent protein kinase holoenzyme complexCellular ComponentIDA (17420273)
GO:0001726ruffleCellular ComponentIDA (10205165)
GO:0005737cytoplasmCellular ComponentIDA (14985467)
GO:0016740transferase activityMolecular FunctionIEA
GO:0030332cyclin bindingMolecular FunctionIPI (8114739)
GO:0005524ATP bindingMolecular FunctionIEA
GO:0004693cyclin-dependent protein kinase activityMolecular FunctionIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0050680negative regulation of epithelial cell proliferationBiological ProcessIMP (14985467)
GO:0048146positive regulation of fibroblast proliferationBiological ProcessIMP (17420273)
GO:0045668negative regulation of osteoblast differentiationBiological ProcessIDA (15254224)
GO:0045646regulation of erythrocyte differentiationBiological ProcessIMP (12833137)
GO:0043697cell dedifferentiationBiological ProcessIMP (12861051)
GO:0000080G1 phase of mitotic cell cycleBiological ProcessIEP (8114739)
GO:0042063gliogenesisBiological ProcessIMP (12861051)
GO:0010468regulation of gene expressionBiological ProcessIMP (17420273)
GO:0010468regulation of gene expressionBiological ProcessIDA (15254224)
GO:0007049cell cycleBiological ProcessIEA
GO:0006468protein amino acid phosphorylationBiological ProcessIEA
GO:0001954positive regulation of cell-matrix adhesionBiological ProcessIDA (10205165)
GO:0051301cell divisionBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:1021
HGNC:1777
Ensembl:ENSG00000105810
MIM:603368
HPRD:04533
HuGE Navigator:1021
dbSNP:CDK6
GeneCard:CDK6
AceView:CDK6