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Gene Information
Gene ID:10233
Symbol:LRRC23
Full Name:leucine rich repeat containing 23
Alias:LRPB7
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12p13
Physical Location:6884212-6893666 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D12S99  5434815
Region:3434815-7434815
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006992.2NP_008923.1NC_000012.10 range: 6884212..6893666
NM_201650.1NP_964013.1NC_000012.10 range: 6884212..6893666
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0003674molecular_functionMolecular FunctionND
GO:0005515protein bindingMolecular FunctionIEA
GO:0008150biological_processBiological ProcessND
Other Database Cross Links
NCBI Entrez Gene:10233
HGNC:19138
Ensembl:ENSG00000010626
MIM:
HPRD:09818
HuGE Navigator:10233
dbSNP:LRRC23
GeneCard:LRRC23
AceView:LRRC23