ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Lars2

Full Name:

leucyl-tRNA synthetase, mitochondrial

Alias:

AI035546|Kiaa0028|LEURS

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 F|9 70.6 cM

Physical Location:

123276057-123371781 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 23395 Symbol (Name): LARS2 (leucyl-tRNA synthetase 2, mitochondrial)

Ortholog Status:

The human GeneID 23395 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Etact2	Alcohol Stimulated Activity	9	61	51-71 (cM)	3.6	4.30E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_153168.2	NP_694808.1	NC_000075.5 range: 123276057..123371781

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (14651853)
GO:0005739	mitochondrion	Cellular Component	RCA (16141072)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004823	leucine-tRNA ligase activity	Molecular Function	RCA (16141072)
GO:0004812	aminoacyl-tRNA ligase activity	Molecular Function	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0006412	translation	Biological Process	IEA
GO:0006418	tRNA aminoacylation for protein translation	Biological Process	IEA
GO:0006429	leucyl-tRNA aminoacylation	Biological Process	RCA (16141072)