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Gene Information
Gene ID:10280
Symbol:OPRS1
Full Name:opioid receptor, sigma 1
Alias:FLJ25585|MGC3851|SIGMAR1|SR-BP1
Organism:Homo sapiens (Human)
Chromosome:9
Genetic Location:9p13.3
Physical Location:34624718-34627767 on NC_000009.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original IDNo. of PublicationsPhenotype
OPRS11Alcoholism
OPRS11Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005866.2NP_005857.1NC_000009.10 range: 34624718..34627767, complement
NM_147157.1NP_671513.1NC_000009.10 range: 34624718..34627767, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0042995cell projectionCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0012511monolayer-surrounded lipid storage bodyCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentTAS (8954936)
GO:0005886plasma membraneCellular ComponentIEA
GO:0005789endoplasmic reticulum membraneCellular ComponentIEA
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005640nuclear outer membraneCellular ComponentIEA
GO:0005637nuclear inner membraneCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0008144drug bindingMolecular FunctionTAS (8954936)
GO:0004872receptor activityMolecular FunctionIEA
GO:0000247C-8 sterol isomerase activityMolecular FunctionIEA
GO:0006696ergosterol biosynthetic processBiological ProcessIEA
GO:0006869lipid transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:10280
HGNC:8157
Ensembl:ENSG00000147955
MIM:601978
HPRD:03580
HuGE Navigator:10280
dbSNP:OPRS1
GeneCard:OPRS1
AceView:OPRS1