ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

IKZF1

Full Name:

IKAROS family zinc finger 1 (Ikaros)

Alias:

Hs.54452|IK1|IKAROS|LYF1|PRO0758|ZNFN1A1|hIk-1

Organism:

Homo sapiens (Human)

Chromosome:

7

Genetic Location:

7p13-p11.1

Physical Location:

50411724-50440292 on NC_000007.12

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		W01226
Fold Change:		1.67
P Value:		0.02
Tissue:		Prefrontal cortex

Dataset Information

Name:		15816859
Method:		Microarray
Tissue:		Prefrontal cortex and nucleus accumbens
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:		Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006060.3	NP_006051.1	NC_000007.12 range: 50411724..50440292

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	TAS (8543809)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0007498	mesoderm development	Biological Process	TAS (8543809)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: