ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Etv5

Full Name:

ets variant gene 5

Alias:

1110005E01Rik|8430401F14Rik|ERM

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

16 B1

Physical Location:

22381385-22439642 on NC_000082.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2119 Symbol (Name): ETV5 (ets variant gene 5 (ets-related molecule))

Ortholog Status:

The human GeneID 2119 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		AW214004
Fold Change:		-1.5, -1.5, NC, -1.4
Note:		4 fold changes are from C57BL/6J trial 1, C57BL/6J trial 2, DBA/2J trial 1, DBA/2J trial 2

Dataset Information

Name:		15002731
Method:		Microarray
Tissue:		Whole brain
Phenotype:		Acute ethanol response
Publication:		Treadwell et al. Neurochem Res. (2004) Microarray analysis of mouse brain gene expression following acute ethanol treatment. PubMed
Summary:		We have analyzed the expression of approximately 24,000 genes using oligonucleotide microarrays to examine the brain expression profiles in two strains of inbred mice, C57BL/6J and DBA/2J, following exposure to an acute dose of ethanol. Our screen identified 61 genes responding to the ethanol treatment beyond a 1.5-fold threshold, with 46 genes altered in both mouse strains and 15 altered in only one strain.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_023794.2	NP_076283.2	NC_000082.5 range: 22381385..22439642, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IC (15466854)
GO:0003677	DNA binding	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0016563	transcription activator activity	Molecular Function	IDA (15466854)
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0009887	organ morphogenesis	Biological Process	IDA (12871699)
GO:0045941	positive regulation of transcription	Biological Process	IDA (15466854)