ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

CEL

Full Name:

carboxyl ester lipase (bile salt-stimulated lipase)

Alias:

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

9q34.3

Physical Location:

134927185-134937068 on NC_000009.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

CEL

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001807.3	NP_001798.2	NC_000009.10 range: 134927185..134937068

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	EXP (2318975\|7350912\|7350913)
GO:0005737	cytoplasm	Cellular Component	ISS
GO:0004771	sterol esterase activity	Molecular Function	EXP (7350913)
GO:0016787	hydrolase activity	Molecular Function	TAS (2265692)
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0047372	acylglycerol lipase activity	Molecular Function	EXP (2318975\|7350912)
GO:0008201	heparin binding	Molecular Function	NAS (7578248)
GO:0004771	sterol esterase activity	Molecular Function	NAS (12031288)
GO:0004806	triacylglycerol lipase activity	Molecular Function	NAS (2265692)
GO:0044258	intestinal lipid catabolic process	Biological Process	NAS (7578248)
GO:0030299	cholesterol absorption	Biological Process	NAS (12031288)
GO:0030157	pancreatic juice secretion	Biological Process	ISS
GO:0030157	pancreatic juice secretion	Biological Process	IDA (1854805)
GO:0018350	protein amino acid esterification	Biological Process	NAS (7578248)
GO:0006707	cholesterol catabolic process	Biological Process	ISS
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0006641	triacylglycerol metabolic process	Biological Process	IC (2265692)
GO:0006707	cholesterol catabolic process	Biological Process	IDA (12031288)
GO:0006707	cholesterol catabolic process	Biological Process	NAS (7578248)
GO:0009062	fatty acid catabolic process	Biological Process	NAS (7578248)