ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ZMYND11

Full Name:

zinc finger, MYND domain containing 11

Alias:

BRAM1|BS69|MGC111056|RP11-486H9.1

Organism:

Homo sapiens (Human)

Chromosome:

10

Genetic Location:

10p14

Physical Location:

170642-290576 on NC_000010.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Linkage Dataset

Marker

LOD

P value

Location (bp)

D10S249

270791

Region:		1-2270791
Phenotype:		Alcoholism phenotype along with age, gender, and P300 or constraint
Name:		15211641
Method:		Linkage
Publication:		Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:		A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_006624.3	NP_006615.1	NC_000010.9 range: 170642..290576
NM_212479.1	NP_997644.1	NC_000010.9 range: 170642..290576

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (7621829)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0045786	negative regulation of cell cycle	Biological Process	IEA
GO:0008283	cell proliferation	Biological Process	TAS (7621829)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	TAS (7621829)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000015171

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: