ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Mthfs

Full Name:

5, 10-methenyltetrahydrofolate synthetase

Alias:

1110034I12Rik|2310020H23Rik|AI119695

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

9 E3.1

Physical Location:

89106027-89135062 on NC_000075.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 10588 Symbol (Name): MTHFS (5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase))

Ortholog Status:

The human GeneID 10588 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		16783646
Method:		Microarray and QTL
Tissue:		Whole brain
Phenotype:		Alcohol preference, acute functional tolerance
Publication:		Saba et al. Mamm Genome. (2006) Candidate genes and their regulatory elements: alcohol preference and tolerance. PubMed
Summary:		Identified of 8 candidate genes for the trait of alcohol preference and 22 candidate genes for acute functional tolerance

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_026829.2	NP_081105.1	NC_000075.5 range: 89106027..89135062

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005542	folic acid binding	Molecular Function	IEA
GO:0016874	ligase activity	Molecular Function	IEA
GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity	Molecular Function	IEA
GO:0009396	folic acid and derivative biosynthetic process	Biological Process	IEA