ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ME3

Full Name:

malic enzyme 3, NADP(+)-dependent, mitochondrial

Alias:

FLJ34862

Organism:

Homo sapiens (Human)

Chromosome:

11

Genetic Location:

11cen-q22.3

Physical Location:

85829797-86061074 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

ME3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001014811.1	NP_001014811.1	NC_000011.8 range: 85829797..86061074, complement
NM_006680.2	NP_006671.2	NC_000011.8 range: 85829797..86061074, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	TAS (7818469)
GO:0005759	mitochondrial matrix	Cellular Component	IEA
GO:0004470	malic enzyme activity	Molecular Function	IEA
GO:0004473	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	Molecular Function	IDA (7818469)
GO:0051287	NAD binding	Molecular Function	IEA
GO:0048037	cofactor binding	Molecular Function	TAS (7818469)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0009060	aerobic respiration	Biological Process	TAS (7818469)
GO:0006800	oxygen and reactive oxygen species metabolic process	Biological Process	TAS (7818469)
GO:0006108	malate metabolic process	Biological Process	IEA
GO:0006108	malate metabolic process	Biological Process	IDA (7818469)
GO:0006090	pyruvate metabolic process	Biological Process	IDA (7818469)
GO:0055114	oxidation reduction	Biological Process	IDA (7818469)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000151376

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: