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Gene Information
Gene ID:10966
Symbol:RAB40B
Full Name:RAB40B, member RAS oncogene family
Alias:FLJ42385|RAR|SEC4L
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q25.3
Physical Location:78208237-78249801 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S928  77846128
Region:75846128-78774742
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006822.1NP_006813.1NC_000017.9 range: 78208237..78249801, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0005525GTP bindingMolecular FunctionIEA
GO:0006512ubiquitin cycleBiological ProcessIEA
GO:0007264small GTPase mediated signal transductionBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:10966
HGNC:18284
Ensembl:ENSG00000141542
MIM:
HPRD:11472
HuGE Navigator:10966
dbSNP:RAB40B
GeneCard:RAB40B
AceView:RAB40B