ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

F11

Full Name:

coagulation factor XI

Alias:

1600027G01Rik|AI503996|Cf11|FXI

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B1.1|8 25.0 cM

Physical Location:

46326523-46347384 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2160 Symbol (Name): F11 (coagulation factor XI (plasma thromboplastin antecedent))

Ortholog Status:

The human GeneID 2160 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_028066.1	NP_082342.1	NC_000074.5 range: 46326523..46347384, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0003805	coagulation factor XIa activity	Molecular Function	IEA
GO:0004252	serine-type endopeptidase activity	Molecular Function	IEA
GO:0008201	heparin binding	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0006508	proteolysis	Biological Process	IEA
GO:0007596	blood coagulation	Biological Process	IEA
GO:0030193	regulation of blood coagulation	Biological Process	IMP (16533887)