ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Cyp11b1

Full Name:

cytochrome P450, family 11, subfamily b, polypeptide 1

Alias:

AA389061|CPN1|Cyp11b|Cyp11b-1|FHI

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 D3|15 44.9 cM

Physical Location:

74665324-74672048 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 1584 Symbol (Name): CYP11B1 (cytochrome P450, family 11, subfamily B, polypeptide 1)

Ortholog Status:

The human GeneID 1584 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001033229.2	NP_001028401.1	NC_000081.5 range: 74665324..74672048, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (10224232)
GO:0004497	monooxygenase activity	Molecular Function	IEA
GO:0005506	iron ion binding	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0047783	corticosterone 18-monooxygenase activity	Molecular Function	IDA (1686470\|8645611)
GO:0006704	glucocorticoid biosynthetic process	Biological Process	IDA (1686470\|8645611)
GO:0006704	glucocorticoid biosynthetic process	Biological Process	IMP (10224232)