ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Glra3

Full Name:

glycine receptor, alpha 3 subunit

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 B2|8 26.0 cM

Physical Location:

58419621-58604148 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 8001 Symbol (Name): GLRA3 (glycine receptor, alpha 3)

Ortholog Status:

The human GeneID 8001 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_080438.2	NP_536686.2	NC_000074.5 range: 58419621..58604148

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0045211	postsynaptic membrane	Cellular Component	IEA
GO:0045202	synapse	Cellular Component	IEA
GO:0030054	cell junction	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0031404	chloride ion binding	Molecular Function	IEA
GO:0030594	neurotransmitter receptor activity	Molecular Function	IEA
GO:0016934	extracellular-glycine-gated chloride channel activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005254	chloride channel activity	Molecular Function	IEA
GO:0005230	extracellular ligand-gated ion channel activity	Molecular Function	RCA (12466851)
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0004890	GABA-A receptor activity	Molecular Function	RCA (12466851)
GO:0006811	ion transport	Biological Process	RCA (12466851)
GO:0006810	transport	Biological Process	RCA (12466851)
GO:0006821	chloride transport	Biological Process	IEA