ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Amhr2

Full Name:

anti-Mullerian hormone type 2 receptor

Alias:

MGC141312|MISIIR|Misrii

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F3|15 57.4 cM

Physical Location:

102275850-102285060 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 269 Symbol (Name): AMHR2 (anti-Mullerian hormone receptor, type II)

Ortholog Status:

The human GeneID 269 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_144547.1	NP_653130.1	NC_000081.5 range: 102275850..102285060

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8895659)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0005887	integral to plasma membrane	Cellular Component	ISS (11960012)
GO:0030145	manganese ion binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005026	transforming growth factor beta receptor activity, type II	Molecular Function	ISO
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	Molecular Function	RCA (12466851)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005024	transforming growth factor beta receptor activity	Molecular Function	TAS (8895659)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007548	sex differentiation	Biological Process	IMP (8895659)
GO:0007179	transforming growth factor beta receptor signaling pathway	Biological Process	TAS (8895659)
GO:0007179	transforming growth factor beta receptor signaling pathway	Biological Process	ISO
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA