ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Nr3c2

Full Name:

nuclear receptor subfamily 3, group C, member 2

Alias:

MR|Mlr

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C1|8 35.0 cM

Physical Location:

79426406-79767537 on NC_000074.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 4306 Symbol (Name): NR3C2 (nuclear receptor subfamily 3, group C, member 2)

Ortholog Status:

The human GeneID 4306 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001083906.1	NP_001077375.1	NC_000074.5 range: 79426406..79767537

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005783	endoplasmic reticulum	Cellular Component	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0008289	lipid binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (11809749)
GO:0005496	steroid binding	Molecular Function	IDA (11809749)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0003707	steroid hormone receptor activity	Molecular Function	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006883	cellular sodium ion homeostasis	Biological Process	IMP (9689096)
GO:0007588	excretion	Biological Process	IMP (9689096)
GO:0006350	transcription	Biological Process	IEA