ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

AKR1C4

Full Name:

aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

Alias:

3-alpha-HSD|C11|CDR|CHDR|DD4|HAKRA|MGC22581

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10p15-p14

Physical Location:

5228797-5250911 on NC_000010.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

AKR1C4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001818.2	NP_001809.2	NC_000010.9 range: 5228797..5250911

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	TAS (2187532)
GO:0005829	cytosol	Cellular Component	EXP (11158055)
GO:0004033	aldo-keto reductase activity	Molecular Function	EXP (11158055)
GO:0047042	3-alpha-hydroxysteroid dehydrogenase (B-specific) activity	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0015125	bile acid transmembrane transporter activity	Molecular Function	TAS (8172617)
GO:0009055	electron carrier activity	Molecular Function	TAS (8172617)
GO:0004033	aldo-keto reductase activity	Molecular Function	TAS (7650035)
GO:0047743	chlordecone reductase activity	Molecular Function	IEA
GO:0015721	bile acid and bile salt transport	Biological Process	TAS (8172617)
GO:0008209	androgen metabolic process	Biological Process	TAS (7650035)