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Gene Information
Gene ID:1124
Symbol:CHN2
Full Name:chimerin (chimaerin) 2
Alias:ARHGAP3|BCH|MGC138360|RHOGAP3
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7p15.3
Physical Location:29200645-29520468 on NC_000007.12
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CHN2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original ID1:BG563170
Fold Change:0.61
P Value:0.02
Tissue:Nucleus accumbens
Dataset Information
Name:15816859
Method:Microarray
Tissue:Prefrontal cortex and nucleus accumbens
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed
Summary:Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001039936.1NP_001035025.1NC_000007.12 range: 29200645..29520468
NM_004067.2NP_004058.1NC_000007.12 range: 29200645..29520468
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005070SH3/SH2 adaptor activityMolecular FunctionTAS (8175705)
GO:0005096GTPase activator activityMolecular FunctionTAS (7614486)
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0019992diacylglycerol bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0007242intracellular signaling cascadeBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:1124
HGNC:1944
Ensembl:ENSG00000106069
MIM:602857
HPRD:04173
HuGE Navigator:1124
dbSNP:CHN2
GeneCard:CHN2
AceView:CHN2