ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Abl2

Full Name:

v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Alias:

AA536808|Abll|Arg

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 G3-H1|1 82.1 cM

Physical Location:

158489179-158579749 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 27 Symbol (Name): ABL2 (v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene))

Ortholog Status:

The human GeneID 27 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009595.2	NP_033725.2	NC_000067.5 range: 158489179..158579749

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component	TAS (10995551)
GO:0015629	actin cytoskeleton	Cellular Component	IDA (11752434)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0030145	manganese ion binding	Molecular Function	IDA (12748290)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IDA (12748290)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0018108	peptidyl-tyrosine phosphorylation	Biological Process	IDA (12748290)
GO:0007155	cell adhesion	Biological Process	IEA
GO:0007015	actin filament organization	Biological Process	IDA (11752434)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0051017	actin filament bundle formation	Biological Process	IDA (11752434)