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Gene Information
Gene ID:1142
Symbol:CHRNB3
Full Name:cholinergic receptor, nicotinic, beta 3
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8p11.2
Physical Location:42671718-42711365 on NC_000008.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:CHRNB3
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
CHRNB31Alcoholism
CHRNB31Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000749.3NP_000740.1NC_000008.9 range: 42671718..42711365
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0005886plasma membraneCellular ComponentIEA
GO:0005892nicotinic acetylcholine-gated receptor-channel complexCellular ComponentTAS (7690916)
GO:0030054cell junctionCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentNAS (8906617)
GO:0030594neurotransmitter receptor activityMolecular FunctionIEA
GO:0015267channel activityMolecular FunctionTAS (7690916)
GO:0004889nicotinic acetylcholine-activated cation-selective channel activityMolecular FunctionTAS (7690916)
GO:0005230extracellular ligand-gated ion channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0007165signal transductionBiological ProcessTAS (7690916)
GO:0006811ion transportBiological ProcessIEA
GO:0007271synaptic transmission, cholinergicBiological ProcessTAS (7690916)
Other Database Cross Links
NCBI Entrez Gene:1142
HGNC:1963
Ensembl:ENSG00000147432
MIM:118508
HPRD:00336
HuGE Navigator:1142
dbSNP:CHRNB3
GeneCard:CHRNB3
AceView:CHRNB3