ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Acvr1b

Full Name:

activin A receptor, type 1B

Alias:

6820432J04|ActR-IB|ActRIB|Acvrlk4|Alk4|SKR2

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 F2|15 60.4 cM

Physical Location:

101004555-101043031 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 91 Symbol (Name): ACVR1B (activin A receptor, type IB)

Ortholog Status:

The human GeneID 91 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_007395.3	NP_031421.1	NC_000081.5 range: 101004555..101043031

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	RCA (12466851)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (9512518)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0030145	manganese ion binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0048185	activin binding	Molecular Function	IPI (7577669)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005024	transforming growth factor beta receptor activity	Molecular Function	RCA (12466851)
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	RCA (12466851)
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	Molecular Function	TAS (9512518)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0009790	embryonic development	Biological Process	IMP (9512518)
GO:0007498	mesoderm development	Biological Process	ISS (9012495)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	TAS (9512518)
GO:0001942	hair follicle development	Biological Process	IMP (16127153)
GO:0001701	in utero embryonic development	Biological Process	IMP (15485907\|16564040)
GO:0006468	protein amino acid phosphorylation	Biological Process	RCA (12466851)