| Gene Information |
| Gene ID: | | 1149 |
| Symbol: | | CIDEA |
| Full Name: | | cell death-inducing DFFA-like effector a |
| Alias: | | CIDE-A |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 18 |
| Genetic Location: | | 18p11.21|18 |
| Physical Location: | | 12244317-12267593 on NC_000018.8 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Linkage Dataset | | Marker | LOD | P value | Location (bp) | |
| D18S53 | | | 11482730 | | Region: | | 9482730-13482730 | | Phenotype: | | Alcoholism phenotype along with age, gender, and P300 or constraint | | Name: | | 15211641 | | Method: | | Linkage | | Publication: | | Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed | | Summary: | | A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb). |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005622 | intracellular | Cellular Component | IEA | |
| GO:0005634 | nucleus | Cellular Component | ISS (17080483) | |
| GO:0005737 | cytoplasm | Cellular Component | ISS (17080483) | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0042803 | protein homodimerization activity | Molecular Function | ISS (17080483) | |
| GO:0050710 | negative regulation of cytokine secretion | Biological Process | IMP (15919794) | |
| GO:0043066 | negative regulation of apoptosis | Biological Process | ISS (17080483) | |
| GO:0032720 | negative regulation of tumor necrosis factor production | Biological Process | IMP (15919794) | |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | Biological Process | ISS (17080483) | |
| GO:0008632 | apoptotic program | Biological Process | ISS (9564035) | |
| GO:0008630 | DNA damage response, signal transduction resulting in induction of apoptosis | Biological Process | TAS (9564035) | |
| GO:0008219 | cell death | Biological Process | ISS (17080483) | |
| GO:0006915 | apoptosis | Biological Process | IEA | |
| GO:0006309 | DNA fragmentation during apoptosis | Biological Process | TAS (9564035) | |
| GO:0050995 | negative regulation of lipid catabolic process | Biological Process | IMP (15919794) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 1149 |
| HGNC: | | 1976 |
| Ensembl: | | ENSG00000176194 |
| MIM: | | 604440 |
| HPRD: | | 08380 |
| HuGE Navigator: | | 1149 |
| dbSNP: | | CIDEA |
| GeneCard: | | CIDEA |
| AceView: | | CIDEA |
