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Gene Information
Gene ID:114901
Symbol:Argbp2
Full Name:Arg/Abl-interacting protein ArgBP2
Organism:Rattus norvegicus (Rat)
Chromosome:16
Genetic Location:16q11
Physical Location:49722538-49926410 on NC_005115.2, complement
Gene Type:protein-coding
Human Ortholog:This gene has no human ortholog.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Argbp2
Fold Change:1.22
Tissue:Amygdala
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_053770.1NP_446222.1NC_005115.2 range: 49722538..49926410, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0003676nucleic acid bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0007242intracellular signaling cascadeBiological ProcessIPI (10521485)
Other Database Cross Links
NCBI Entrez Gene:114901
RGD:620061
Ensembl:ENSRNOG00000013391
dbSNP:Argbp2