ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Adam2

Full Name:

a disintegrin and metallopeptidase domain 2

Alias:

AI323749|Ftnb|Ph30-beta

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

14 D1|14 28.0 cM

Physical Location:

66646165-66696569 on NC_000080.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2515 Symbol (Name): ADAM2 (ADAM metallopeptidase domain 2 (fertilin beta))

Ortholog Status:

The human GeneID 2515 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws5/Alcw7	Chronic Alcohol Withdrawal	14		24-48 (cM)	4.2	6.00E-05	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009618.2	NP_033748.2	NC_000080.5 range: 66646165..66696569, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0004222	metalloendopeptidase activity	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008237	metallopeptidase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (15194697)
GO:0007229	integrin-mediated signaling pathway	Biological Process	IEA
GO:0007155	cell adhesion	Biological Process	IEA
GO:0008542	visual learning	Biological Process	IMP (16504143)
GO:0006508	proteolysis	Biological Process	IEA
GO:0030534	adult behavior	Biological Process	IMP (16504143)