ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Adcy8

Full Name:

adenylate cyclase 8

Alias:

AC8|AW060868

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 D1|15 37.5 cM

Physical Location:

64530596-64753857 on NC_000081.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 114 Symbol (Name): ADCY8 (adenylate cyclase 8 (brain))

Ortholog Status:

The human GeneID 114 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_009623.2	NP_033753.2	NC_000081.5 range: 64530596..64753857, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016020	membrane	Cellular Component	IEA
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016849	phosphorus-oxygen lyase activity	Molecular Function	IEA
GO:0016829	lyase activity	Molecular Function	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0004016	adenylate cyclase activity	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0009190	cyclic nucleotide biosynthetic process	Biological Process	IEA
GO:0007242	intracellular signaling cascade	Biological Process	IEA
GO:0006171	cAMP biosynthetic process	Biological Process	IEA